{"product_id":"nedl2-rabbit-pab-es6915","title":"NEDL2 rabbit pAb - ES6915","description":"\u003cp\u003eNEDL2 rabbit pAb\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: ES6915-50, ES6915-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: function:E3 ubiquitin-protein ligase that mediates ubiquitination of TP73. Acts to stabilize TP73 and enhance activation of transcription by TP73., pathway:Protein modification; protein ubiquitination., similarity:Contains 1 C2 domain., similarity:Contains 1 HECT (E6AP-type E3 ubiquitin-protein ligase) domain., similarity:Contains 2 WW domains., subunit:Interacts with TP73., tissue specificity:Predominantly expressed in adult brain, lung and heart.,\u003c\/p\u003e \n\n\u003cp\u003eAlternate Name: HECW2; KIAA1301; NEDL2; E3 ubiquitin-protein ligase HECW2; HECT; C2 and WW domain-containing protein 2; NEDD4-like E3 ubiquitin-protein ligase 2\u003c\/p\u003e\n\n\u003cp\u003eSource: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB; ELISA\u003c\/p\u003e\n\n\u003cp\u003eDilution: Western Blot: 1\/500 - 1\/2000. ELISA: 1\/10000. Not yet tested in other applications.\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human; Rat; Mouse;\u003c\/p\u003e \n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human HECW2. AA range:481-530\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: -20°C\/1 year\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eObserved Band (KD): 140-150kD\u003c\/p\u003e\n\n\u003cp\u003eHuman Gene ID: 57520\u003c\/p\u003e\n\n\u003cp\u003eHuman SWISS Prot NO: Q9P2P5\u003c\/p\u003e\n\n\u003cp\u003eSubcellular Location: Cytoplasm. Cytoplasm, cytoskeleton, spindle.\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"ELK Bio","offers":[{"title":"50μL","offer_id":45202320720051,"sku":"ES6915-50","price":207.2,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45202320752819,"sku":"ES6915-100","price":347.2,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/download_360x_4985824d-5bd9-4f2f-a474-93dc6206e366.png?v=1767126521","url":"https:\/\/afsbio.com\/products\/nedl2-rabbit-pab-es6915","provider":"AFSBio Inc.","version":"1.0","type":"link"}