{"product_id":"nefl-monoclonal-antibody-bt-mca3400","title":"NEFL Monoclonal Antibody - BT-MCA3400","description":"\u003cp\u003eNEFL Monoclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Number: BT-MCA3400-50, BT-MCA3400-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: Neurofilaments are type IV intermediate filament heteropolymers composed of light, medium, and heavy chains. Neurofilaments comprise the axoskeleton and they functionally maintain the neuronal caliber. They may also play a role in intracellular transport to axons and dendrites. This gene encodes the light chain neurofilament protein. Mutations in this gene cause Charcot-Marie-Tooth disease types 1F (CMT1F) and 2E (CMT2E), disorders of the peripheral nervous system that are characterized by distinct neuropathies. A pseudogene has been identified on chromosome Y.\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Neuroscience\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: NEFL\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, IHC, ICC, FCM\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human\u003c\/p\u003e\n\n\u003cp\u003eClonality: Monoclonal\u003c\/p\u003e\n\n\u003cp\u003eClone ID: 1H3\u003c\/p\u003e\n\n\u003cp\u003eHost: Mouse\u003c\/p\u003e\n\n\u003cp\u003eIsotype: Mouse IgG1\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: NEFL\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Purified recombinant fragment of human NEFL expressed in E. Coli.\u003c\/p\u003e\n\n\u003cp\u003eStorage: 4°C|-20°C for long term storage\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Ascitic fluid containing 0.03% sodium azide\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight (Da): 62kDa\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: P07196\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: NFL, NF-L, NF68, CMT1F, CMT2E\u003c\/p\u003e\n\n\u003cp\u003eGeneID: 4747\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"50μL","offer_id":45238583361715,"sku":"BT-MCA3400-50","price":308.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45238583394483,"sku":"BT-MCA3400-100","price":448.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_987efd5f-cb5a-4e88-8793-5b269cff50d8.png?v=1769382802","url":"https:\/\/afsbio.com\/products\/nefl-monoclonal-antibody-bt-mca3400","provider":"AFSBio Inc.","version":"1.0","type":"link"}