{"product_id":"neil2-polyclonal-antibody-bt-ap11795","title":"NEIL2 Polyclonal Antibody - BT-AP11795","description":"\u003cp\u003eNEIL2 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BT-AP11795-20, BT-AP11795-50, BT-AP11795-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: NEIL2 belongs to a class of DNA glycosylases homologous to the bacterial Fpg\/Nei family. These glycosylases initiate the first step in base excision repair by cleaving bases damaged by reactive oxygen species and introducing a DNA strand break via the associated lyase reaction (Bandaru et al., 2002\u003c\/p\u003e \n\n\u003cp\u003eResearch Areas: Epigenetics and nuclear signaling\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: NEIL2\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, ELISA\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: Endonuclease 8-like 2\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C for 1 year\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Human: Q969S2; Mouse: Q6R2P8\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: Endonuclease 8-like 2;EC 3.2.2.-;EC 4.2.99.18;DNA glycosylase\/AP lyase Neil2;DNA-;apurinic or apyrimidinic site lyase Neil2;Endonuclease VIII-like 2;Nei homolog 2;NEH2;Nei-like protein\u003c\/p\u003e\n\n\u003cp\u003eGeneID: Human: 252969\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"20μL","offer_id":45239238492339,"sku":"BT-AP11795-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"50μL","offer_id":45239238525107,"sku":"BT-AP11795-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45239238557875,"sku":"BT-AP11795-100","price":385.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_4b4d7c1e-b9a0-43f4-b0c7-774f4faee8ad.png?v=1769391025","url":"https:\/\/afsbio.com\/products\/neil2-polyclonal-antibody-bt-ap11795","provider":"AFSBio Inc.","version":"1.0","type":"link"}