{"product_id":"nesprin-3-polyclonal-antibody-bt-ap05891","title":"Nesprin-3 Polyclonal Antibody - BT-AP05891","description":"\u003cp\u003eNesprin-3 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BT-AP05891-20, BT-AP05891-50, BT-AP05891-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: Component of SUN-protein-containing multivariate complexes also called LINC complexes which link the nucleoskeleton and cytoskeleton by providing versatile outer nuclear membrane attachment sites for cytoskeletal filaments. Involved in the maintenance of nuclear organization and structural integrity. Probable anchoring protein which tethers the nucleus to the cytoskeleton by binding PLEC which can associate with the intermediate filament system.\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Signal Transduction\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: SYNE3\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, IF, ELISA\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: Nesprin-3 Antibody\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C for 1 year\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight (Da): 112216\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Human: Q6ZMZ3; Mouse: Q4FZC9\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: SYNE3; C14orf49; Nesprin-3; Nuclear envelope spectrin repeat protein 3\u003c\/p\u003e\n\n\u003cp\u003eGeneID: Human: 161176; Mouse: 212073\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"20μL","offer_id":45239731191987,"sku":"BT-AP05891-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"50μL","offer_id":45239731224755,"sku":"BT-AP05891-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45239731257523,"sku":"BT-AP05891-100","price":385.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_adc1420f-9aea-43c8-a023-7c187c475f9f.png?v=1769398585","url":"https:\/\/afsbio.com\/products\/nesprin-3-polyclonal-antibody-bt-ap05891","provider":"AFSBio Inc.","version":"1.0","type":"link"}