{"product_id":"nesprin-3-rabbit-pab-es4963","title":"Nesprin-3 rabbit pAb - ES4963","description":"\u003cp\u003eNesprin-3 rabbit pAb\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: ES4963-50, ES4963-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: function:Involved in the maintenance of nuclear organization and structural integrity. Probable anchoring protein which theters the nucleus to the cytoskeleton by binding PLEC1\/Plectin which can associate with the intermediate filament system., similarity:Belongs to the nesprin family., similarity:Contains 1 KASH domain., similarity:Contains 2 spectrin repeats., subcellular location:Located at the rough reticulum endoplasmic (RER) in some cells., subunit:Interacts with actin-binding domain of PLEC1\/plectin.,\u003c\/p\u003e \n\n\u003cp\u003eAlternate Name: SYNE3; C14orf49; Nesprin-3; Nuclear envelope spectrin repeat protein 3\u003c\/p\u003e\n\n\u003cp\u003eSource: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB; IF; ELISA\u003c\/p\u003e\n\n\u003cp\u003eDilution: Western Blot: 1\/500 - 1\/2000. Immunofluorescence: 1\/200 - 1\/1000. ELISA: 1\/40000. Not yet tested in other applications.\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human; Mouse\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human C14orf49. AA range:169-218\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: -20°C\/1 year\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eObserved Band (KD): 115kD\u003c\/p\u003e\n\n\u003cp\u003eHuman Gene ID: 161176\u003c\/p\u003e\n\n\u003cp\u003eHuman SWISS Prot NO: Q6ZMZ3\u003c\/p\u003e\n\n\u003cp\u003eSubcellular Location: Nucleus outer membrane; Single-pass type IV membrane protein. Nucleus envelope. Rough endoplasmic reticulum.\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"ELK Bio","offers":[{"title":"50μL","offer_id":45202223333555,"sku":"ES4963-50","price":207.2,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45202223366323,"sku":"ES4963-100","price":347.2,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/download_360x_a3f787bc-7745-4164-a17c-097cd860f19d.png?v=1767124557","url":"https:\/\/afsbio.com\/products\/nesprin-3-rabbit-pab-es4963","provider":"AFSBio Inc.","version":"1.0","type":"link"}