{"product_id":"neuropilin-1-rabbit-monoclonal-antibody-bs40088","title":"Neuropilin 1 Rabbit Monoclonal Antibody -BS40088","description":"\u003cp\u003eNeuropilin 1 Rabbit Monoclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eProduct: Rabbit IgG, 1mg\/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2.\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50µl, 100µl\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BS40088-50, BS40088-100\u003c\/p\u003e\n\n\u003cp\u003eSwiss-Prot: O14786\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eNeuropilin 1 Rabbit Monoclonal Antibody -BS40088\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, IHC ICC\/IF, IP, FC\u003c\/p\u003e\n\n\u003cp\u003eAll Applications: WB 1:500~1:2000 IHC 1:50~1:200 ICC\/IF 1:50~1:200 IP 1:50 FC 1:50\u003c\/p\u003e\n\n\u003cp\u003eBackground: The membrane-bound isoform 1 is a receptor involved in the development of the cardiovascular system, in angiogenesis, in the formation of certain neuronal circuits and in organogenesis outside the nervous system. It mediates the chemorepulsant activity of semaphorins. It binds to semaphorin 3A, The PLGF-2 isoform of PGF, The VEGF-165 isoform of VEGF and VEGF-B. Coexpression with KDR results in increased VEGF-165 binding to KDR as well as increased chemotaxis. It may regulate VEGF-induced angiogenesis.The soluble isoform 2 binds VEGF-165 and appears to inhibit its binding to cells.\u003c\/p\u003e\n\n\u003cp\u003ePurification and Purity: Affinity-chromatography\u003c\/p\u003e\n\n\u003cp\u003eSpecificity: Neuropilin 1 Antibody detects endogenous levels of total Neuropilin 1\u003c\/p\u003e\n\n\u003cp\u003eBioworld Molecular Weight: ~ 120 kDa\u003c\/p\u003e\n\n\u003cp\u003eNote: For research use only, not for use in diagnostic procedure.\u003c\/p\u003e\n\n\u003cp\u003eExtra Notes: Western blot (WB) analysis of Neuropilin 1 Rabbit monoclonal antibody at 1:500 dilution\u003cbr\u003e\n Lane 1: PC12 whole cell lysate (30ug) \u003cbr\u003e\n Lane 2: 3T3-L1 whole cell lysate (30ug) \u003cbr\u003e\n Lane 3: A549 whole cell lysate (30ug), Immunohistochemical analysis of paraffin-embedded human melanoma, using Neuropilin 1 Antibody.\u003c\/p\u003e\n\n\u003cp\u003eAlternative Name: A5 protein; BDCA4; CD304Neuropilin1; NP1; NPN1; NRP1; VEGF165RNEL like protein 1; Blood dendritic cell antigen 4\u003c\/p\u003e\n\n\n\u003cp\u003eImmunogen: A synthesized peptide derived from human Neuropilin 1\u003c\/p\u003e\n\n\u003cp\u003eModification: Unmodified\u003c\/p\u003e\n\n\u003cp\u003eConjugate: Unconjugated\u003c\/p\u003e","brand":"BioWorld","offers":[{"title":"50µl","offer_id":42957266485427,"sku":"BS40088-50","price":276.71,"currency_code":"CAD","in_stock":true},{"title":"100µl","offer_id":42957266518195,"sku":"BS40088-100","price":490.83,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/thumbnail_d1447bac803ec9be_11-14-09-19-51_2945c070-d558-4f00-b6d3-ef3aa4761185.jpg?v=1705144230","url":"https:\/\/afsbio.com\/products\/neuropilin-1-rabbit-monoclonal-antibody-bs40088","provider":"AFSBio Inc.","version":"1.0","type":"link"}