{"product_id":"nfat2-polyclonal-antibody-e-ab-60332","title":"NFAT2 Polyclonal Antibody - E-AB-60332","description":"\u003cp\u003eNFAT2 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 60μL, 120μL, 200μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: E-AB-60332-60, E-AB-60332-120, E-AB-60332-200\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: NFAT2\u003c\/p\u003e\n\n\u003cp\u003eTarget Synonym: NF-ATC; NF-ATc1.2; NFAT2; NFATc; NFATC1\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Cancer, Cardiovascular, Epigenetics and Nuclear Signaling, Immunology, Signal Transduction\u003c\/p\u003e\n\n\u003cp\u003eConjugation: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eSpecies Reactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eApplication: WB, IHC\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n \n\n\u003cp\u003eUNIProt ID: O95644\u003c\/p\u003e\n\n\u003cp\u003eBackground: The product of this gene is a component of the nuclear factor of activated T cells DNA-binding transcription complex. This complex consists of at least two components: a preexisting cytosolic component that translocates to the nucleus upon T cell receptor (TCR) stimulation, and an inducible nuclear component. Proteins belonging to this family of transcription factors play a central role in inducible gene transcription during immune response. The product of this gene is an inducible nuclear component. It functions as a major molecular target for the immunosuppressive drugs such as cyclosporin A. Multiple alternatively spliced transcript variants encoding distinct isoforms have been identified for this gene. Different isoforms of this protein may regulate inducible expression of different cytokine genes.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1mg\/mL\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Recombinant fusion protein of human NFAT2 (NP_765978.1).\u003c\/p\u003e\n\n\u003cp\u003eBuffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.\u003c\/p\u003e\n\n\u003cp\u003ePurification Method: Affinity purification\u003c\/p\u003e\n\n\u003cp\u003eDilution: WB \t1:500-1:3000   IHC \t1:50-1:200\u003c\/p\u003e\n\n\u003cp\u003eCalculated MW: 38kDa\/74- 88kDa\/100-101kDa\u003c\/p\u003e\n\n\u003cp\u003eObserved MW: 78kDa\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C\/One year. Avoid freeze \/ thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eShipping: Ice bag\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"60μL","offer_id":43146049224883,"sku":"E-AB-60332-60","price":280.0,"currency_code":"CAD","in_stock":true},{"title":"120μL","offer_id":43146049257651,"sku":"E-AB-60332-120","price":448.0,"currency_code":"CAD","in_stock":true},{"title":"200μL","offer_id":43146049290419,"sku":"E-AB-60332-200","price":742.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_b965d2f8-7389-4501-b1db-3e30f90d3bbe.png?v=1710290616","url":"https:\/\/afsbio.com\/products\/nfat2-polyclonal-antibody-e-ab-60332","provider":"AFSBio Inc.","version":"1.0","type":"link"}