{"product_id":"nfatc4-polyclonal-antibody-bt-ap05957","title":"NFATc4 Polyclonal Antibody - BT-AP05957","description":"\u003cp\u003eNFATc4 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BT-AP05957-20, BT-AP05957-50, BT-AP05957-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: NFATC4 encodes a member of the nuclear factor of activated T cells (NFAT) protein family. Nuclear factor of activated T-cells cytoplasmic 4 is part of a DNA-binding transcription complex. This complex consists of at least two components: a preexisting cytosolic component that translocates to the nucleus upon T cell receptor stimulation and an inducible nuclear component. NFAT proteins are activated by the calmodulin-dependent phosphatase, calcineurin. The encoded protein plays a role in the inducible expression of cytokine genes in T cells, especially in the induction of interleukin-2 and interleukin-4. Alternative splicing results in multiple transcript variants.\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Immunology\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: NFATC4\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, IHC-p, IF, ELISA\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: NFATc4 Antibody\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C for 1 year\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight (Da): 95473\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Human: Q14934; Mouse: Q8K120\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: NFATC4; NFAT3; Nuclear factor of activated T-cells; cytoplasmic 4; NF-ATc4; NFATc4; T-cell transcription factor NFAT3; NF-AT3\u003c\/p\u003e\n\n\u003cp\u003eGeneID: Human: 4776; Mouse: 73181\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"20μL","offer_id":45239738794163,"sku":"BT-AP05957-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"50μL","offer_id":45239738826931,"sku":"BT-AP05957-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45239738859699,"sku":"BT-AP05957-100","price":385.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_d362b119-5c15-49c5-a9a8-f9a604060ed9.png?v=1769398669","url":"https:\/\/afsbio.com\/products\/nfatc4-polyclonal-antibody-bt-ap05957","provider":"AFSBio Inc.","version":"1.0","type":"link"}