{"product_id":"nfe2-polyclonal-antibody-bt-ap09118","title":"NFE2 Polyclonal Antibody - BT-AP09118","description":"\u003cp\u003eNFE2 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BT-AP09118-20, BT-AP09118-50, BT-AP09118-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: Required for activity at the locus control region (LCR) upstream of the globin gene complexes. Requires p18 NF-E2 for binding to the NF-E2 motif. May play a role in all aspects of hemoglobin production: globin synthesis| heme synthesis| and the procurement of iron.|Belongs to the bZIP family.|Belongs to the bZIP family. CNC subfamily.|Contains 1 bZIP domain.|subunit:Interacts with MLL2; leading to activate transcription of the beta-globin locus (By similarity). Heterodimer of p45 NF-E2 and p18 NF-E2. Forms high affinity heterodimer with MAFG; the interaction promotes erythropoiesis.|tissue specificity:Expressed in hematopoietic cells and also in colon and testis.|\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Epigenetics and nuclear signaling\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: NFE2\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, ELISA\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: Transcription factor NF-E2 45 kDa subunit\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C for 1 year\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Human: Q16621; Mouse: Q07279; Rat: Q6AYT2\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: Transcription factor NF-E2 45 kDa subunit (Leucine zipper protein NF-E2;Nuclear factor; erythroid-derived 2 45 kDa subunit;p45 NF-E2)\u003c\/p\u003e\n\n\u003cp\u003eGeneID: Human: 4778\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"20μL","offer_id":45238988177587,"sku":"BT-AP09118-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"50μL","offer_id":45238988210355,"sku":"BT-AP09118-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45238988243123,"sku":"BT-AP09118-100","price":385.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_8411129a-079b-42a3-ad29-f6c30bf3024c.png?v=1769387630","url":"https:\/\/afsbio.com\/products\/nfe2-polyclonal-antibody-bt-ap09118","provider":"AFSBio Inc.","version":"1.0","type":"link"}