{"product_id":"nfib-nf1b2-monoclonal-antibody-mb9382","title":"NFIB NF1B2 Monoclonal Antibody-MB9382","description":"\u003cp\u003eNFIB NF1B2 Monoclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50µl, 100µl\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: MB9382-50, MB9382-100\u003c\/p\u003e\n\n\u003cp\u003eProduct: Mouse IgG1, 1mg\/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2\u003c\/p\u003e\n\n\u003cp\u003eSwiss-Prot: O00712(Human) P97863(Mouse)\u003c\/p\u003e\n\n\u003cp\u003eHost: Mouse\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, IHC FC\u003c\/p\u003e\n\n\u003cp\u003eAll Applications: WB:1:500-1:2,000\u003cbr\u003e\nIHC:1:50-1:200\u003cbr\u003e\nFC:1:50-1:100\u003c\/p\u003e\n\n\u003cp\u003eBackground: NF-1, also designated CTF, consists of a family of CCAAT box binding proteins that stimulate DNA replication and activate transcription. Analysis of human NF-1 messenger RNA has revealed two forms of the NF-1 protein arising from an alternate splicing of a single NF-1 gene. NF-1 binds its consensus DNA element as a homodimer via an amino-terminal DNA binding domain, and activates transcription through a putatively novel, proline-rich, carboxy terminal transactivation domain. The NF-1 protein has been shown to recognize and bind the adenovirus type 2 promoter and activate transcription of herpes simplex virus thymidine kinase genes. The NF-1 consensus element has been found in the upstream promoter region of myriad eukaryotic genes, including that of Ha-Ras, α-globin, HSP 70, GRP 78, Histone H1, myelin basic protein and in the Xenopus laevis vitellogenin gene promoter.\u003c\/p\u003e\n\n\u003cp\u003ePurification and Purity: ProG affinity purified.\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze \/ thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eSpecificity: NFIB NF1B2 monoclonal antibody detects endogenous levels of NFIB NF1B2 protein.\u003c\/p\u003e\n\n\u003cp\u003eBioworld Molecular Weight: 47\/55 kDa\u003c\/p\u003e\n\n\u003cp\u003eNote: For research use only, not for use in diagnostic procedure.\u003c\/p\u003e\n\n\u003cp\u003eExtra Notes: Western blot analysis of NFIB\/NF1B2 on SH-SY5Y using anti-NFIB\/NF1B2 antibody at 1\/1,000 dilution., Immunohistochemical analysis of paraffin-embedded rat heart tissue using anti-NFIB\/NF1B2 antibody. Counter stained with hematoxylin.\u003c\/p\u003e\n\n\u003cp\u003eAlternative Name: NF1-B, Nuclear factor 1\/B, CTF, NF-I\/B, NFI-B, NFIB, CCAAT Box Binding Transcription Factor, CCAAT-box-binding transcription factor, CTF, HMGIC\/NFIB, NF-I\/B, NF1-B, NF1B, NF1B2, NFI-B, NFI-RED, Nfib, NFIB, NFIB2, NFIB3, Nuclear factor 1 B-type, Nuclear factor 1\/B, Nuclear Factor 1B, Nuclear Factor I B, Nuclear factor I\/B, TGGCA Binding Protein, TGGCA-binding protein, TRANSCRIPTION FACTOR NFIB,\u003c\/p\u003e \n\n\u003cp\u003eImmunogen: Recombinant full length protein corresponding to human NFIB\/NF1B2.\u003c\/p\u003e\n\n\u003cp\u003eConjugate: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eModification: Unmodified\u003c\/p\u003e","brand":"BioWorld","offers":[{"title":"50µl","offer_id":42987076878515,"sku":"MB9382-50","price":424.94,"currency_code":"CAD","in_stock":true},{"title":"100µl","offer_id":42987076911283,"sku":"MB9382-100","price":655.54,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/thumbnail_d1447bac803ec9be_11-14-09-19-51_721fb62a-d43b-4b2a-b28e-8878bce3d4a9.jpg?v=1706008655","url":"https:\/\/afsbio.com\/products\/nfib-nf1b2-monoclonal-antibody-mb9382","provider":"AFSBio Inc.","version":"1.0","type":"link"}