{"product_id":"nfkb2-monoclonal-antibody-bt-mca2051","title":"NFKB2 Monoclonal Antibody - BT-MCA2051","description":"\u003cp\u003eNFKB2 Monoclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Number: BT-MCA2051-50, BT-MCA2051-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: This gene encodes a subunit of the transcription factor complex nuclear factor-kappa-B (NFkB). The NFkB complex is expressed in numerous cell types and functions as a central activator of genes involved in inflammation and immune function. The protein encoded by this gene can function as both a transcriptional activator or repressor depending on its dimerization partner. The p100 full-length protein is co-translationally processed into a p52 active form. Chromosomal rearrangements and translocations of this locus have been observed in B cell lymphomas, some of which may result in the formation of fusion proteins. There is a pseudogene for this gene on chromosome 18. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2013]\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Cell Biology\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: NFKB2\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse\u003c\/p\u003e\n\n\u003cp\u003eClonality: Monoclonal\u003c\/p\u003e\n\n\u003cp\u003eClone ID: 5E6A12\u003c\/p\u003e\n\n\u003cp\u003eHost: Mouse\u003c\/p\u003e\n\n\u003cp\u003eIsotype: Mouse IgG1\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: NFKB2\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Purified recombinant fragment of human NFKB2 (AA: 712-900) expressed in E. Coli.\u003c\/p\u003e\n\n\u003cp\u003eStorage: 4°C|-20°C for long term storage\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Purified antibody in PBS with 0.05% sodium azide\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight (Da): 96.7kDa\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Q00653\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: p52, p100, H2TF1, LYT10, CVID10, LYT-10, NF-kB2, p49\/p100\u003c\/p\u003e\n\n\u003cp\u003eGeneID: 4791\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"50μL","offer_id":45238421356723,"sku":"BT-MCA2051-50","price":308.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45238421389491,"sku":"BT-MCA2051-100","price":448.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_0b816402-bc85-497c-9dc9-afd0355573ad.png?v=1769380491","url":"https:\/\/afsbio.com\/products\/nfkb2-monoclonal-antibody-bt-mca2051","provider":"AFSBio Inc.","version":"1.0","type":"link"}