{"product_id":"nfkbid-polyclonal-antibody-e-ab-13857","title":"NFKBID Polyclonal Antibody - E-AB-13857","description":"\u003cp\u003eNFKBID Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 60μL, 120μL, 200μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: E-AB-13857-60, E-AB-13857-120, E-AB-13857-200\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: NFKBID\u003c\/p\u003e\n\n\u003cp\u003eTarget Synonym: I-kappa-B-delta; IkappaBdelta; IkappaBNS; IkB-delta; IKBD; IKBNS; NF-kappa-B inhibitor delta; NFKBID; Nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor delta; T-cell activation NFKB-like protein; TA-NFKBH\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Epigenetics and Nuclear Signaling, Immunology, Signal Transduction\u003c\/p\u003e\n\n\u003cp\u003eConjugation: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eSpecies Reactivity: Human, Mouse\u003c\/p\u003e\n\n\u003cp\u003eApplication: WB, IHC, ELISA\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n \n\n\u003cp\u003eUNIProt ID: Q8NI38\u003c\/p\u003e\n\n\u003cp\u003eBackground: May regulate the expression of IL-2, IL-6, and other cytokines through regulation on NF-kappa-B activity. Functions in the regulation of inflammatory responses. May also regulate TCR-induced negative selection of thymocytes.IκBNS, the nuclear IκB-like protein encoded by Nfkbid, is required for the development of marginal zone and peritoneal B-1 B cells and additionally required for extrafollicular antibody responses to T-independent and -dependent immunogens.IκBNS has been identified as a member of the IκB family of NF-κB inhibitors, which undergoes induction upon TCR signaling. IκBNS mediates both positive and negative gene regulation, depending on individual cell type and\/or cytokine.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 0.4 mg\/mL\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Recombinant protein of human NFKBID\u003c\/p\u003e\n\n\u003cp\u003eBuffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4\u003c\/p\u003e\n\n\u003cp\u003ePurification Method: Affinity purification\u003c\/p\u003e\n\n\u003cp\u003eDilution: WB 1:200-1:1000, IHC 1:25-1:100\u003c\/p\u003e\n\n\u003cp\u003eCalculated MW: 33kDa\u003c\/p\u003e\n\n \n\n\u003cp\u003eStorage: -20°C\/One year. Avoid freeze \/ thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eShipping: Ice bag\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"60μL","offer_id":43136324927667,"sku":"E-AB-13857-60","price":200.2,"currency_code":"CAD","in_stock":true},{"title":"120μL","offer_id":43136324960435,"sku":"E-AB-13857-120","price":336.0,"currency_code":"CAD","in_stock":true},{"title":"200μL","offer_id":43136324993203,"sku":"E-AB-13857-200","price":558.6,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_37c53f99-6ab5-4a61-be61-4aab1e481caa.png?v=1709989153","url":"https:\/\/afsbio.com\/products\/nfkbid-polyclonal-antibody-e-ab-13857","provider":"AFSBio Inc.","version":"1.0","type":"link"}