{"product_id":"nhp2-rabbit-pab-a5991","title":"NHP2 Rabbit pAb - A5991","description":"\u003cp\u003eNHP2 Rabbit pAb\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: A5991-20, A5991-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: This gene is a member of the H\/ACA snoRNPs (small nucleolar ribonucleoproteins) gene family. snoRNPs are involved in various aspects of rRNA processing and modification and have been classified into two families: C\/D and H\/ACA. The H\/ACA snoRNPs also include the DKC1, NOLA1 and NOLA3 proteins. These four H\/ACA snoRNP proteins localize to the dense fibrillar components of nucleoli and to coiled (Cajal) bodies in the nucleus. Both 18S rRNA production and rRNA pseudouridylation are impaired if any one of the four proteins is depleted. The four H\/ACA snoRNP proteins are also components of the telomerase complex. This gene encodes a protein related to Saccharomyces cerevisiae Nhp2p. Alternative splicing results in multiple transcript variants.\u003c\/p\u003e\n\n\u003cp\u003eCategory: Polyclonal Antibodies\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, ELISA\u003c\/p\u003e\n\n\u003cp\u003eCross-reactivity: Human, Rat\u003c\/p\u003e\n\n\u003cp\u003eProtein Weight: 17kDa\u003c\/p\u003e\n\n\u003cp\u003eObserved Molecular Weight: 17kDa\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Recombinant protein (or fragment) .\u003c\/p\u003e\n\n\u003cp\u003eSpecies: Human\u003c\/p\u003e\n\n\u003cp\u003eGeneID: 55651\u003c\/p\u003e\n\n\u003cp\u003eSWISS: Q9NX24\u003c\/p\u003e\n\n\u003cp\u003eAlternate Names: DKCB2; NHP2P; NOLA2; NHP2\u003c\/p\u003e\n\n\u003cp\u003eSource: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003ePurity: Affinity purification\u003c\/p\u003e\n\n\u003cp\u003eStorage: Store at -20℃. Avoid freeze \/ thaw cycles. Buffer: PBS with 0.01% thimerosal, 50% glycerol, pH 7.3.\u003c\/p\u003e\n\n\u003cp\u003eRecommended Dilutions: WB, 1:500 - 1:2000 ELISA, Recommended starting concentration is 1 μg\/mL. Please optimize the concentration based on your specific assay requirements.\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Epigenetics Nuclear Signaling, RNA Binding.\u003c\/p\u003e\n\n\u003cp\u003eNCBI Alias: NHP2\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"ABclonal","offers":[{"title":"20uL","offer_id":45189973180595,"sku":"A5991-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"100uL","offer_id":45189973213363,"sku":"A5991-100","price":417.2,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/download_498c8c7b-1942-4f73-a416-e538ca36b1f0.png?v=1766439082","url":"https:\/\/afsbio.com\/products\/nhp2-rabbit-pab-a5991","provider":"AFSBio Inc.","version":"1.0","type":"link"}