{"product_id":"nhrf1-polyclonal-antibody-bt-ap13945","title":"NHRF1 Polyclonal Antibody - BT-AP13945","description":"\u003cp\u003eNHRF1 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BT-AP13945-20, BT-AP13945-50, BT-AP13945-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: This gene encodes a sodium\/hydrogen exchanger regulatory cofactor. The protein interacts with and regulates various proteins including the cystic fibrosis transmembrane conductance regulator and G-protein coupled receptors such as the beta2-adrenergic receptor and the parathyroid hormone 1 receptor. The protein also interacts with proteins that function as linkers between integral membrane and cytoskeletal proteins. The protein localizes to actin-rich structures including membrane ruffles| microvilli| and filopodia. Mutations in this gene result in hypophosphatemic nephrolithiasis\/osteoporosis type 2| and loss of heterozygosity of this gene is implicated in breast cancer.\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Signal transduction; Cancer; Tags and cell markers\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: SLC9A3R1\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, ELISA\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Rat, Mouse\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: Na\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C for 1 year\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Human: O14745; Mouse: P70441; Rat: Q9JJ19\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: Na;+\/H;+ exchange regulatory cofactor NHE-RF1;NHERF-1;Ezrin-radixin-moesin-binding phosphoprotein 50;EBP50;Regulatory cofactor of Na;+\/H;+ exchanger;Sodium-hydrogen exchanger regulatory f\u003c\/p\u003e\n\n\u003cp\u003eGeneID: Human: 9368\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"20μL","offer_id":45239034183859,"sku":"BT-AP13945-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"50μL","offer_id":45239034216627,"sku":"BT-AP13945-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45239034249395,"sku":"BT-AP13945-100","price":385.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_1f5f552e-6829-4a94-a91c-1a6abd1650aa.png?v=1769388196","url":"https:\/\/afsbio.com\/products\/nhrf1-polyclonal-antibody-bt-ap13945","provider":"AFSBio Inc.","version":"1.0","type":"link"}