{"product_id":"nkiamre-polyclonal-antibody-bt-ap06042","title":"NKIAMRE Polyclonal Antibody - BT-AP06042","description":"\u003cp\u003eNKIAMRE Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BT-AP06042-20, BT-AP06042-50, BT-AP06042-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: The protein encoded by CDKL3 (cyclin dependent kinase like 3) is a member of cyclin-dependent protein kinase (CDK) family. CDK family members are highly similar to the gene products of Saccharomyces cerevisiae cdc28, and Schizosaccharomyces pombe cdc2, and are known to be important regulators of cell cycle progression. CDKL3 was identified as a gene absent in leukemic patients with chromosome 5q deletion. This loss may be an important determinant of dysmyelopoiesis. Alternative splicing results in multiple transcript variants encoding different isoforms.\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Cell Biology\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: CDKL3\u003c\/p\u003e\n\n\u003cp\u003eApplications: IHC-p, WB, ELISA\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: NKIAMRE Antibody\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C for 1 year\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight (Da): 67514\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Human: Q8IVW4; Mouse: Q8BLF2\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: CDKL3; NKIAMRE; Cyclin-dependent kinase-like 3; Serine\/threonine-protein kinase NKIAMRE\u003c\/p\u003e\n\n\u003cp\u003eGeneID: Human: 51265\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"20μL","offer_id":45239748427955,"sku":"BT-AP06042-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"50μL","offer_id":45239748460723,"sku":"BT-AP06042-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45239748493491,"sku":"BT-AP06042-100","price":385.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_b73ee120-6574-471c-8505-5a5292b0fa97.png?v=1769398763","url":"https:\/\/afsbio.com\/products\/nkiamre-polyclonal-antibody-bt-ap06042","provider":"AFSBio Inc.","version":"1.0","type":"link"}