{"product_id":"nkp46-rabbit-polyclonal-antibody-es2965","title":"NKp46 Rabbit Polyclonal Antibody - ES2965","description":"\u003cp\u003eNKp46 Rabbit Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: ES2965-50, ES2965-100\u003c\/p\u003e\n\n\u003cp\u003eLead times: 1-2 weeks, if manufacturer has product in stock\u003c\/p\u003e\n\n\u003cp\u003eManufacturer\/Ship Location: China\u003c\/p\u003e\n\n\u003cp\u003eBackground: function:Cytotoxicity-activating receptor that may contribute to the increased efficiency of activated natural killer (NK) cells to mediate tumor cell lysis.,PTM:N-glycosylated.,PTM:O-glycosylated.,similarity:Belongs to the natural cytotoxicity receptor (NCR) family.,similarity:Contains 2 Ig-like (immunoglobulin-like) domains.,subunit:Interacts with CD3Z and FCER1G.,tissue specificity:Selectively expressed by both resting and activated NK cells.,\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Rat, Mouse,\u003c\/p\u003e \n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, ELISA\u003c\/p\u003e\n\n\u003cp\u003eAlternate Names: NCR1, LY94, Natural cytotoxicity triggering receptor 1, Lymphocyte antigen 94 homolog, NK cell-activating receptor, Natural killer cell p46-related protein, NK-p46, NKp46, hNKp46, CD antigen CD335\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human NCR1. AA range:145-194\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eTarget: NKp46\u003c\/p\u003e\n\n\u003cp\u003eSpecificity: NKp46 Polyclonal Antibody detects endogenous levels of NKp46 protein.\u003c\/p\u003e\n\n\u003cp\u003eDilution: Western Blot: 1\/500 - 1\/2000. ELISA: 1\/10000. Not yet tested in other applications.\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml,\u003c\/p\u003e\n\n\u003cp\u003eFormlation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eExpression: Selectively expressed by both resting and activated NK cells,\u003c\/p\u003e\n\n\u003cp\u003eObserved Band (KD): 40kD\u003c\/p\u003e\n\n\u003cp\u003eFields: Natural killer cell mediated cytotoxicity\u003c\/p\u003e\n\n\u003cp\u003eFunction: Function: Cytotoxicity-activating receptor that may contribute to the increased efficiency of activated natural killer (NK) cells to mediate tumor cell lysis\u003cbr\u003e\nPTM: N-glycosylated\u003cbr\u003e\nPTM: O-glycosylated\u003cbr\u003e\nSimilarity: Belongs to the natural cytotoxicity receptor (NCR) family\u003cbr\u003e\nSimilarity: Contains 2 Ig-like (immunoglobulin-like) domains\u003cbr\u003e\nSubunit: Interacts with CD3Z and FCER1G\u003cbr\u003e\nTissue Specificity: Selectively expressed by both resting and activated NK cells\u003c\/p\u003e\n\n\n\u003cp\u003eSubcellular Location: Cell membrane, Single-pass type I membrane protein\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: -20°C\/1 year\u003c\/p\u003e\n\n\u003cp\u003eGene Name: NCR1\u003c\/p\u003e\n\n\u003cp\u003eProtein Name: Natural cytotoxicity triggering receptor 1\u003c\/p\u003e\n\n\u003cp\u003eMouse SwissProt Number: Q8C567\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"ELK Biotechnology","offers":[{"title":"50μL","offer_id":46314239656115,"sku":"ES2965-50","price":186.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":46314239688883,"sku":"ES2965-100","price":372.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/elk_antibodies_d75295e2-ffc1-4e0f-a3e7-87715c8983a9.jpg?v=1793190507","url":"https:\/\/afsbio.com\/products\/nkp46-rabbit-polyclonal-antibody-es2965","provider":"AFSBio Inc.","version":"1.0","type":"link"}