{"product_id":"nkrf-mouse-monoclonal-antibody-mb4030","title":"NKRF Mouse Monoclonal Antibody - MB4030","description":"\u003cp\u003eNKRF Mouse Monoclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 25μl, 100μl\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: MB4030-25, MB4030-100\u003c\/p\u003e\n\n\u003cp\u003eLead times: 1-2 weeks, if manufacturer has product in stock\u003c\/p\u003e\n\n\u003cp\u003eManufacturer\/Ship Location: China\u003c\/p\u003e\n\n\u003cp\u003eBackground: NF-κB Repressing Factor (NKRF) is a constitutively expressed transcription factor that binds to the negative regμlatory element within the promotor region of many genes that are transactivated by NF-κB (1). Indeed, research studies have found NKRF to repress transcription of IL-8\/CXCL8, iNOS, CXCL10, and IFN-γ (2-4). In addition to regμlating the expression of pro-inflammatory factors, NKRF has been shown to play a role in cell survival in the context of proteotoxic stress, through the regμlation of rRNA processing and ribosome biogenesis (5).\u003c\/p\u003e\n\n\u003cp\u003eCategory: Primary Antibody\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse\u003c\/p\u003e\n\n\u003cp\u003eHost: Mouse\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB\u003c\/p\u003e\n\n\u003cp\u003eAlternate Names: NF-kappa-B-repressing factor, NFkB-repressing factor, Protein ITBA4, NKRF, ITBA4, NRF, 9606 NCBIHomo sapiens (Human)\u003c\/p\u003e \n\n\u003cp\u003eClonality: Monoclonal\u003c\/p\u003e\n\n\u003cp\u003eConjugate: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eModification: Unmodified\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Human recombinant protein fragment corresponding to amino acids 1-296 of human NKRF(NP_060014) produced in E.coli.\u003c\/p\u003e\n\n\u003cp\u003eDilution: WB 1:2000\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from mouse ascites fluids or tissue cμlture supernatant by affinity-chromatography using epitope-specific immunogen and the purity is \u0026gt; 95% (by SDS-PAGE).\u003c\/p\u003e\n\n\u003cp\u003eSpecificity: IgG2a\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight: ~ 90 kDa\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eSwissProt: O15226\u003c\/p\u003e\n\n\u003cp\u003eProduct: 1mg\/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Bioworld","offers":[{"title":"25μl","offer_id":45945964429491,"sku":"MB4030-25","price":289.5,"currency_code":"CAD","in_stock":true},{"title":"100μl","offer_id":45945964462259,"sku":"MB4030-100","price":642.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/Bioworld_Antibody_Image_6ca33534-2486-4e91-ac84-9e0d75778258.jpg?v=1788363539","url":"https:\/\/afsbio.com\/products\/nkrf-mouse-monoclonal-antibody-mb4030","provider":"AFSBio Inc.","version":"1.0","type":"link"}