{"product_id":"nlrp1-polyclonal-antibody-e-ab-93147","title":"NLRP1 Polyclonal Antibody - E-AB-93147","description":"\u003cp\u003eNLRP1 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 60μL, 120μL, 200μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: E-AB-93147-60, E-AB-93147-120, E-AB-93147-200\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: NLRP1\u003c\/p\u003e\n\n\u003cp\u003eTarget Synonym: NLRP1; AIADK; CARD7; CIDED; CLR17.1; DEFCAP; DEFCAP-L\/S; MSPC; NAC; NALP1; PP1044; SLEV1; VAMAS1\u003c\/p\u003e\n\n \n\n\u003cp\u003eConjugation: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eSpecies Reactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eApplication: WB, IHC, IF\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n \n\n\u003cp\u003eUNIProt ID: Q9C000\u003c\/p\u003e\n\n\u003cp\u003eBackground: This gene encodes a member of the Ced-4 family of apoptosis proteins. Ced-family members contain a caspase recruitment domain (CARD) and are known to be key mediators of programmed cell death. The encoded protein contains a distinct N-terminal pyrin-like motif, which is possibly involved in protein-protein interactions. This protein interacts strongly with caspase 2 and weakly with caspase 9. Overexpression of this gene was demonstrated to induce apoptosis in cells. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene, but the biological validity of some variants has not been determined.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1mg\/mL\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Recombinant fusion protein of human NLRP1\u003c\/p\u003e\n\n\u003cp\u003eBuffer: PBS with 0.05% proclin300, 50% glycerol, pH7.3.\u003c\/p\u003e\n\n\u003cp\u003ePurification Method: Affinity purification\u003c\/p\u003e\n\n\u003cp\u003eDilution: WB 1:500-1:2000, IHC 1:50-1:200, IF 1:50-1:200\u003c\/p\u003e\n\n\u003cp\u003eCalculated MW: 46kDa\/83kDa\/154-165kDa\u003c\/p\u003e\n\n\u003cp\u003eObserved MW: 160KDa\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C\/One year. Avoid freeze \/ thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eShipping: Ice bag\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"60μL","offer_id":43145987195059,"sku":"E-AB-93147-60","price":280.0,"currency_code":"CAD","in_stock":true},{"title":"120μL","offer_id":43145987227827,"sku":"E-AB-93147-120","price":448.0,"currency_code":"CAD","in_stock":true},{"title":"200μL","offer_id":43145987260595,"sku":"E-AB-93147-200","price":742.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_db4e9a74-d1b1-48ae-8832-9aed46cc2710.png?v=1710289316","url":"https:\/\/afsbio.com\/products\/nlrp1-polyclonal-antibody-e-ab-93147","provider":"AFSBio Inc.","version":"1.0","type":"link"}