{"product_id":"nlrp10-polyclonal-antibody-e-ab-16648","title":"NLRP10 Polyclonal Antibody - E-AB-16648","description":"\u003cp\u003eNLRP10 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 60μL, 120μL, 200μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: E-AB-16648-60, E-AB-16648-120, E-AB-16648-200\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: NLRP10\u003c\/p\u003e\n\n\u003cp\u003eTarget Synonym: CLR11.1; NACHT; leucine rich repeat and PYD containing 10; NACHT; LRR and PYD domains containing protein 10; NACHT; LRR and PYD domains-containing protein 10; NAL10; NALP10; NLR family; pyrin domain containing 10; Nlrp10; NOD8; Nucleotide-binding oligomerization domain protein 8; Nucleotide-binding oligomerization domain; leucine rich repeat and pyrin domain containing 10; PAN5; PYNOD\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Cell biology, Immunology\u003c\/p\u003e\n\n\u003cp\u003eConjugation: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eSpecies Reactivity: Human\u003c\/p\u003e\n\n\u003cp\u003eApplication: IHC, ELISA\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eUNIProt ID: Q86W26\u003c\/p\u003e\n\n\u003cp\u003eBackground: Members of the NALP protein family typically contain a NACHT domain, a NACHT-associated domain (NAD), a C-terminal leucine-rich repeat (LRR) region, and an N-terminal pyrin domain (PYD). The protein encoded by this gene belongs to the NALP protein family despite lacking the LRR region. This protein likely plays a regulatory role in the innate immune system. The protein belongs to the signal-induced multiprotein complex, the inflammasome, that activates the pro-inflammatory caspases, caspase-1 and caspase-5. Other experiments indicate that this gene acts as a multifunctional negative regulator of inflammation and apoptosis.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1.2 mg\/mL\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Synthetic peptide of human NLRP10\u003c\/p\u003e\n\n\u003cp\u003eBuffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4\u003c\/p\u003e\n\n\u003cp\u003ePurification Method: Affinity purification\u003c\/p\u003e\n\n\u003cp\u003eDilution: IHC 1:50-1:200\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C\/One year. Avoid freeze \/ thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eShipping: Ice bag\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"60μL","offer_id":43130638270643,"sku":"E-AB-16648-60","price":200.2,"currency_code":"CAD","in_stock":true},{"title":"120μL","offer_id":43130638303411,"sku":"E-AB-16648-120","price":336.0,"currency_code":"CAD","in_stock":true},{"title":"200μL","offer_id":43130638336179,"sku":"E-AB-16648-200","price":558.6,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_3b6589e6-73fe-41fa-9e83-e03991d51f0b.png?v=1709810498","url":"https:\/\/afsbio.com\/products\/nlrp10-polyclonal-antibody-e-ab-16648","provider":"AFSBio Inc.","version":"1.0","type":"link"}