{"product_id":"nlrp3-recombinant-rabbit-monoclonal-antibody-bs45850","title":"NLRP3 Recombinant Rabbit Monoclonal Antibody - BS45850","description":"\u003cp\u003eNLRP3 Recombinant Rabbit mAb\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μl, 100μl\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BS45850-50, BS45850-100\u003c\/p\u003e\n\n\u003cp\u003eLead times: 1-2 weeks, if manufacturer has product in stock\u003c\/p\u003e\n\n\u003cp\u003eManufacturer\/Ship Location: China\u003c\/p\u003e\n\n\u003cp\u003eBackground: Enables DNA-binding transcription factor binding activity and sequence-specific DNA binding activity. Involved in several processes, including positive regμlation of T-helper cell differentiation, positive regμlation of cytokine production, and response to bacterium. Acts upstream of or within several processes, including NLRP3 inflammasome complex assembly, activation of cysteine-type endopeptidase activity involved in apoptotic process, and defense response to virus. Located in cytoplasm and nucleus. Part of NLRP3 inflammasome complex. Is expressed in central nervous system and retina. Used to study CINCA Syndrome, familial cold autoinflammatory syndrome 1, and non-alcoholic fatty liver disease. Human ortholog(s) of this gene implicated in CINCA Syndrome, Muckle-Wells syndrome, autosomal dominant nonsyndromic deafness 34, familial cold autoinflammatory syndrome 1, and urticaria. Orthologous to human NLRP3 (NLR family pyrin domain containing 3). [provided by Alliance of Genome Resources, Apr 2022]\u003c\/p\u003e\n\n\u003cp\u003eCategory: Primary Antibody\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Mouse\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, ICC\/IF, IP\u003c\/p\u003e\n\n\u003cp\u003eAlternate Names: FCU, MWS, FCAS, Cias1, Mmig1, NALP3, Pypaf1, AII\/AVP, AGTAVPRL\u003c\/p\u003e\n\n\u003cp\u003eClonality: Monoclonal\u003c\/p\u003e\n\n\u003cp\u003eConjugate: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eModification: Unmodification\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Recombinant protein of mouse NLRP3\u003c\/p\u003e\n\n\u003cp\u003eDilution: WB: 1:1000 ICC\/IF: 1:50 IP: 1:20\u003c\/p\u003e\n\n\u003cp\u003ePurification: Affinity Purification\u003c\/p\u003e\n\n\u003cp\u003eSpecificity: IgG\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight: 118 kDa\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eSwissProt: Q8R4B8\u003c\/p\u003e\n\n\u003cp\u003eProduct: Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Bioworld","offers":[{"title":"50μl","offer_id":45937215570099,"sku":"BS45850-50","price":424.5,"currency_code":"CAD","in_stock":true},{"title":"100μl","offer_id":45937215602867,"sku":"BS45850-100","price":642.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/Bioworld_Antibody_Image.jpg?v=1788296056","url":"https:\/\/afsbio.com\/products\/nlrp3-recombinant-rabbit-monoclonal-antibody-bs45850","provider":"AFSBio Inc.","version":"1.0","type":"link"}