{"product_id":"nlrp6-polyclonal-antibody-e-ab-93137","title":"NLRP6 Polyclonal Antibody - E-AB-93137","description":"\u003cp\u003eNLRP6 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 60μL, 120μL, 200μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: E-AB-93137-60, E-AB-93137-120, E-AB-93137-200\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: NLRP6\u003c\/p\u003e\n\n\u003cp\u003eTarget Synonym: NLRP6; AVR; CLR11.4; NALP6; NAVR; NAVR\/AVR; PAN3; PYPAF5\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Cell Biology, Immunology, Signal Transduction\u003c\/p\u003e\n\n\u003cp\u003eConjugation: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eSpecies Reactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eApplication: WB\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n \n\n\u003cp\u003eUNIProt ID: P59044\u003c\/p\u003e\n\n\u003cp\u003eBackground: The protein encoded by this gene binds arginine-vasopressin and may be involved in the arginine-vasopressin-mediated regulation of renal salt-water balance. The encoded protein also mediates inflammatory responses in the colon to allow recovery from intestinal epithelial damage and protects against tumorigenesis and the development of colitis. Finally, this protein can increase activation of NF-kappa-B, activation of CASP1 through interaction with ASC, and cAMP accumulation. Two transcript variants encoding different isoforms have been found for this gene.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1mg\/mL\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: A synthetic peptide of human NLRP6\u003c\/p\u003e\n\n\u003cp\u003eBuffer: PBS with 0.05% proclin300, 50% glycerol, pH7.3.\u003c\/p\u003e\n\n\u003cp\u003ePurification Method: Affinity purification\u003c\/p\u003e\n\n\u003cp\u003eDilution: WB 1:500-1:2000\u003c\/p\u003e\n\n\u003cp\u003eCalculated MW: 99kDa\u003c\/p\u003e\n\n\u003cp\u003eObserved MW: 102KDa\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C\/One year. Avoid freeze \/ thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eShipping: Ice bag\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"60μL","offer_id":43146679845043,"sku":"E-AB-93137-60","price":280.0,"currency_code":"CAD","in_stock":true},{"title":"120μL","offer_id":43146679877811,"sku":"E-AB-93137-120","price":448.0,"currency_code":"CAD","in_stock":true},{"title":"200μL","offer_id":43146679910579,"sku":"E-AB-93137-200","price":742.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_bc755a32-822a-48ae-8ded-1d711709a216.png?v=1710299992","url":"https:\/\/afsbio.com\/products\/nlrp6-polyclonal-antibody-e-ab-93137","provider":"AFSBio Inc.","version":"1.0","type":"link"}