{"product_id":"nmbr-rabbit-polyclonal-antibody-es6395","title":"NMBR Rabbit Polyclonal Antibody - ES6395","description":"\u003cp\u003eNMBR Rabbit Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: ES6395-50, ES6395-100\u003c\/p\u003e\n\n\u003cp\u003eLead times: 1-2 weeks, if manufacturer has product in stock\u003c\/p\u003e\n\n\u003cp\u003eManufacturer\/Ship Location: China\u003c\/p\u003e\n\n\u003cp\u003eBackground: This gene encodes a 7-transmembrane G protein-coupled receptor that binds neuromedin B, which is a growth factor and mitogen for gastrointestinal epithelial tissue and for normal and neoplastic lung. This receptor may play a role in smooth muscle contraction, neuronal responses, and the regulation of cell growth. Antagonists of this receptor have a potential therapeutic use in inhibiting tumor cell growth. Polymorphisms in this gene may be associated with a susceptibility for schizophrenia. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Apr 2016],\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, IF, ELISA\u003c\/p\u003e\n\n\u003cp\u003eAlternate Names: NMBR, Neuromedin-B receptor, NMB-R, Epididymis tissue protein Li 185a, Neuromedin-B-preferring bombesin receptor\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human NMBR. AA range:221-270\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eTarget: NMBR\u003c\/p\u003e\n\n\u003cp\u003eSpecificity: NMBR Polyclonal Antibody detects endogenous levels of NMBR protein.\u003c\/p\u003e\n\n\u003cp\u003eDilution: Western Blot: 1\/500 - 1\/2000. Immunofluorescence: 1\/200 - 1\/1000. ELISA: 1\/5000. Not yet tested in other applications.\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml,\u003c\/p\u003e\n\n\u003cp\u003eFormlation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eExpression: Expressed in epididymis (at protein level),\u003c\/p\u003e\n\n\u003cp\u003eObserved Band (KD): 43kD\u003c\/p\u003e\n\n\u003cp\u003eFields: Neuroactive ligand-receptor interaction\u003c\/p\u003e\n\n\u003cp\u003eFunction: Function: Receptor for neuromedin-B\u003cbr\u003e\nSimilarity: Belongs to the G-protein coupled receptor 1 family\u003c\/p\u003e\n\n\n\u003cp\u003eSubcellular Location: Cell membrane, Multi-pass membrane protein\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: -20°C\/1 year\u003c\/p\u003e\n\n\u003cp\u003eGene Name: NMBR\u003c\/p\u003e\n\n\u003cp\u003eProtein Name: Neuromedin-B receptor\u003c\/p\u003e\n\n\u003cp\u003eMouse Gene ID: 18101\u003c\/p\u003e\n\n\u003cp\u003eMouse SwissProt Number: O54799\u003c\/p\u003e\n\n\u003cp\u003eRat Gene ID: 25264\u003c\/p\u003e\n\n\u003cp\u003eRat SwissProt Number: P24053\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"ELK Biotechnology","offers":[{"title":"50μL","offer_id":46313603170483,"sku":"ES6395-50","price":186.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":46313603203251,"sku":"ES6395-100","price":372.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/elk_antibodies_d75295e2-ffc1-4e0f-a3e7-87715c8983a9.jpg?v=1793190507","url":"https:\/\/afsbio.com\/products\/nmbr-rabbit-polyclonal-antibody-es6395","provider":"AFSBio Inc.","version":"1.0","type":"link"}