{"product_id":"nod1-rabbit-polyclonal-antibody-ra33585","title":"NOD1 Rabbit Polyclonal Antibody - RA33585","description":"NOD1 Rabbit Polyclonal Antibody\n\nSizes: 50μL, 100μL\n\nCatalogue Numbers: RA33585-50, RA33585-100\n\nCitations, Manuals and MSDS Available upon request.\n\nBackground: This gene encodes a member of the NOD (nucleotide-binding oligomerization domain) family. This member is a cytosolic protein. It contains an N-terminal caspase recruitment domain (CARD), a centrally located nucleotide-binding domain (NBD), and 10 tandem leucine-rich repeats (LRRs) in its C terminus. The CARD is involved in apoptotic signaling, LRRs participate in protein-protein interactions, and mutations in the NBD may affect the process of oligomerization and subsequent function of the LRR domain. This protein is an intracellular pattern-recognition receptor (PRR) that initiates inflammation in response to a subset of bacteria through the detection of bacterial diaminopimelic acid. Multiple alternatively spliced transcript variants differring in the 5' UTR have been described, but the full-length nature of these variants has not been determined. [provided by RefSeq, Oct 2009],\n\nCondition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.224% sodium azide.\n\nStorage Instructions: -20°C\/1 year\n\nRecommended dilutions: WB 1:500-2000\n\nAlternative Names: Nucleotide-binding oligomerization domain-containing protein 1 (Caspase recruitment domain-containing protein 4) \n\nApplications: WB\n\nSpecies Cross-Reactivity: Human; Mouse\n\nGeneID (Human): 10392\n\nProtein MW (KDa): 105\n\nSWISS: Q9Y239\n\nSource: Rabbit\n\nResearch Use Only","brand":"Reed Bio","offers":[{"title":"50μL","offer_id":45122460516531,"sku":"RA33585-50","price":336.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45122460549299,"sku":"RA33585-100","price":448.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_d6d7e36d-239a-4d4d-a6a0-d306ddc3d992.png?v=1773342509","url":"https:\/\/afsbio.com\/products\/nod1-rabbit-polyclonal-antibody-ra33585","provider":"AFSBio Inc.","version":"1.0","type":"link"}