{"product_id":"nos1-polyclonal-antibody-e-ab-70065","title":"NOS1 Polyclonal Antibody - E-AB-70065","description":"\u003cp\u003eNOS1 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 60μL, 120μL, 200μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: E-AB-70065-60, E-AB-70065-120, E-AB-70065-200\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: NOS1\u003c\/p\u003e\n\n\u003cp\u003eTarget Synonym: 2310005C01Rik; BNOS; Constitutive NOS; EC 1.14.13.39; IHPS 1; IHPS1; N-NOS; NC-NOS; neuronal Nitric Oxide Synthase; Neuronal NOS; Nitric oxide synthase; neuronal; included; Nitric oxide synthase 1 (neuronal); Nitric oxide synthase 1; Nitric oxide synthase; brain; Nitric oxide synthase; penile neuronal; included; NNOS; NO; NOS 1; NOS; NOS type I; NOS-I; NOS1; NOS1; Peptidyl-cysteine S-nitrosylase NOS1\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Cancer, Metabolism, Neuroscience\u003c\/p\u003e\n\n\u003cp\u003eConjugation: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eSpecies Reactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eApplication: WB, IHC\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n \n\n\u003cp\u003eUNIProt ID: P29475,P29476,Q9Z0J4\u003c\/p\u003e\n\n\u003cp\u003eBackground: The protein encoded by this gene belongs to the family of nitric oxide synthases, which synthesize nitric oxide from L-arginine. Nitric oxide is a reactive free radical, which acts as a biologic mediator in several processes, including neurotransmission, and antimicrobial and antitumoral activities. In the brain and peripheral nervous system, nitric oxide displays many properties of a neurotransmitter, and has been implicated in neurotoxicity associated with stroke and neurodegenerative diseases, neural regulation of smooth muscle, including peristalsis, and penile erection. This protein is ubiquitously expressed, with high level of expression in skeletal muscle. Multiple transcript variants that differ in the 5' UTR have been described for this gene but the full-length nature of these transcripts is not known. Additionally, alternatively spliced transcript variants encoding different isoforms (some testis-specific) have been found for this gene.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 350 μg\/mL\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: KLH conjugated Synthetic peptide corresponding to Mouse nNOS\u003c\/p\u003e\n\n\u003cp\u003eBuffer: PBS with 0.02% sodium azide, 1% protective protein and 50% glycerol, pH7.4\u003c\/p\u003e\n\n\u003cp\u003ePurification Method: Affinity purification\u003c\/p\u003e\n\n\u003cp\u003eDilution: WB 1:500-1:2000,  IHC 1:300-1:800\u003c\/p\u003e\n\n\u003cp\u003eCalculated MW: 161kDa\u003c\/p\u003e\n\n\u003cp\u003eObserved MW: 161kDa\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C\/One year. Avoid freeze \/ thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eShipping: Ice bag\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"60μL","offer_id":43146504896691,"sku":"E-AB-70065-60","price":224.0,"currency_code":"CAD","in_stock":true},{"title":"120μL","offer_id":43146504929459,"sku":"E-AB-70065-120","price":364.0,"currency_code":"CAD","in_stock":true},{"title":"200μL","offer_id":43146504962227,"sku":"E-AB-70065-200","price":574.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_1869bf7c-27d4-4b4b-bd9f-d62a859ebf89.png?v=1710296551","url":"https:\/\/afsbio.com\/products\/nos1-polyclonal-antibody-e-ab-70065","provider":"AFSBio Inc.","version":"1.0","type":"link"}