{"product_id":"nox2-gp91phox-polyclonal-antibody-e-ab-93080","title":"NOX2\/gp91phox Polyclonal Antibody - E-AB-93080","description":"\u003cp\u003eNOX2\/gp91phox Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 60μL, 120μL, 200μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: E-AB-93080-60, E-AB-93080-120, E-AB-93080-200\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: NOX2\/gp91phox\u003c\/p\u003e\n\n\u003cp\u003eTarget Synonym: AMCBX2; CGD; GP91-1; GP91-PHOX; GP91PHOX; IMD34; NOX2; p91-PHOX; CYBB\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Cancer, Metabolism, Immunology\u003c\/p\u003e\n\n\u003cp\u003eConjugation: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eSpecies Reactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eApplication: WB\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n \n\n\u003cp\u003eUNIProt ID: P04839\u003c\/p\u003e\n\n\u003cp\u003eBackground: Cytochrome b (-245) is composed of cytochrome b alpha (CYBA) and beta (CYBB) chain. It has been proposed as a primary component of the microbicidal oxidase system of phagocytes. CYBB deficiency is one of five described biochemical defects associated with chronic granulomatous disease (CGD). In this disorder, there is decreased activity of phagocyte NADPH oxidase; neutrophils are able to phagocytize bacteria but cannot kill them in the phagocytic vacuoles. The cause of the killing defect is an inability to increase the cell's respiration and consequent failure to deliver activated oxygen into the phagocytic vacuole.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1mg\/mL\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: A synthetic peptide of human NOX2\/gp91phox\u003c\/p\u003e\n\n\u003cp\u003eBuffer: PBS with 0.01% thiomersal, 50% glycerol, pH7.3.\u003c\/p\u003e\n\n\u003cp\u003ePurification Method: Affinity purification\u003c\/p\u003e\n\n\u003cp\u003eDilution: WB 1:500-1:2000\u003c\/p\u003e\n\n\u003cp\u003eCalculated MW: 65kDa\u003c\/p\u003e\n\n\u003cp\u003eObserved MW: 65kDa\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C\/One year. Avoid freeze \/ thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eShipping: Ice bag\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"60μL","offer_id":43146674995379,"sku":"E-AB-93080-60","price":280.0,"currency_code":"CAD","in_stock":true},{"title":"120μL","offer_id":43146675028147,"sku":"E-AB-93080-120","price":448.0,"currency_code":"CAD","in_stock":true},{"title":"200μL","offer_id":43146675060915,"sku":"E-AB-93080-200","price":742.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_59233354-c5ba-4fa4-a6ae-b9af1ceac087.png?v=1710299887","url":"https:\/\/afsbio.com\/products\/nox2-gp91phox-polyclonal-antibody-e-ab-93080","provider":"AFSBio Inc.","version":"1.0","type":"link"}