{"product_id":"nox3-polyclonal-antibody-bt-ap06117","title":"Nox3 Polyclonal Antibody - BT-AP06117","description":"\u003cp\u003eNox3 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BT-AP06117-20, BT-AP06117-50, BT-AP06117-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: NOX3 encodes a member of the NOX family of NADPH oxidases. These enzymes have the capacity to generate superoxide and other reactive oxygen species (ROS) and transport electrons across the plasma membrane. The ROS generated by family members have been implicated in numerous biological functions including host defense, posttranlational processing of proteins, cellular signaling, regulation of gene expression, and cell differentiation. NADPH oxidase 3 encoded by NOX3 is expressed predominantly in the inner ear and is involved in the biogenesis of otoconia\/otolith, which are crystalline structures of the inner ear involved in the perception of gravity.\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Neuroscience\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: NOX3\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, IHC-p, ELISA\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: Nox3 Antibody\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C for 1 year\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight (Da): 64935\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Human: Q9HBY0; Mouse: Q672J9; Rat: Q672K1\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: NOX3; MOX2; NADPH oxidase 3; Mitogenic oxidase 2; MOX-2; gp91phox homolog 3; GP91-3\u003c\/p\u003e\n\n\u003cp\u003eGeneID: Human: 50508; Mouse: 224480; Rat: 292279\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"20μL","offer_id":45239753441459,"sku":"BT-AP06117-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"50μL","offer_id":45239753474227,"sku":"BT-AP06117-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45239753506995,"sku":"BT-AP06117-100","price":385.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_7619910e-5f82-405b-b918-f2b355999501.png?v=1769398839","url":"https:\/\/afsbio.com\/products\/nox3-polyclonal-antibody-bt-ap06117","provider":"AFSBio Inc.","version":"1.0","type":"link"}