{"product_id":"nox4-polyclonal-antibody-bt-ap11967","title":"NOX4 Polyclonal Antibody - BT-AP11967","description":"\u003cp\u003eNOX4 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BT-AP11967-20, BT-AP11967-50, BT-AP11967-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: This gene encodes a member of the NOX-family of enzymes that functions as the catalytic subunit the NADPH oxidase complex. The encoded protein is localized to non-phagocytic cells where it acts as an oxygen sensor and catalyzes the reduction of molecular oxygen to various reactive oxygen species (ROS). The ROS generated by this protein have been implicated in numerous biological functions including signal transduction, cell differentiation and tumor cell growth. A pseudogene has been identified on the other arm of chromosome 11. Alternative splicing results in multiple transcript variants.\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Cardiovascular; Cell biology; Metabolism; Signal transduction\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: NOX4\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, ELISA\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: NADPH oxidase 4\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C for 1 year\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Human: Q9NPH5; Mouse: Q9JHI8; Rat: Q924V1\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: NADPH oxidase 4;EC 1.6.3.-;Kidney oxidase-1;KOX-1;Kidney superoxide-producing NADPH oxidase;Renal NAD;PH-oxidase\u003c\/p\u003e\n\n\u003cp\u003eGeneID: Human: 50507\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"20μL","offer_id":45239242621107,"sku":"BT-AP11967-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"50μL","offer_id":45239242653875,"sku":"BT-AP11967-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45239242686643,"sku":"BT-AP11967-100","price":385.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_7f6c204c-ae21-4616-9a7e-7a7e4006fdbc.png?v=1769391092","url":"https:\/\/afsbio.com\/products\/nox4-polyclonal-antibody-bt-ap11967","provider":"AFSBio Inc.","version":"1.0","type":"link"}