{"product_id":"nphs2-polyclonal-antibody-e-ab-16657","title":"NPHS2 Polyclonal Antibody - E-AB-16657","description":"\u003cp\u003eNPHS2 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 60μL, 120μL, 200μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: E-AB-16657-60, E-AB-16657-120, E-AB-16657-200\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: NPHS2\u003c\/p\u003e\n\n\u003cp\u003eTarget Synonym: Nephrosis 2; idiopathic; steroid resistant (podocin); nephrosis 2; idiopathic; steroid resistant; NPHS2; NPHS2 gene; PDCN; PODO; Podocin; SRN1\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Cancer, Cell biology, Signal transduction, Tags and Cell markers\u003c\/p\u003e\n\n\u003cp\u003eConjugation: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eSpecies Reactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eApplication: IHC, ELISA\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eUNIProt ID: Q9NP85\u003c\/p\u003e\n\n\u003cp\u003eBackground: This gene encodes the glomerular protein podocin which plays a role in the regulation of glomerular permeability, and acts as a linker between the plasma membrane and the cytoskeleton. Defects in this gene are the cause of autosomal recessive steroid-resistant nephrotic syndrome (SRN). SRN is characterized by onset between three months and five years, resistance to steroid therapy and rapid progression to end-stage renal disease. An alternative splice variant has been described but its full length sequence has not been determined.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1.4 mg\/mL\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Synthetic peptide of human NPHS2\u003c\/p\u003e\n\n\u003cp\u003eBuffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4\u003c\/p\u003e\n\n\u003cp\u003ePurification Method: Affinity purification\u003c\/p\u003e\n\n\u003cp\u003eDilution: IHC 1:50-1:200\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C\/One year. Avoid freeze \/ thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eShipping: Ice bag\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"60μL","offer_id":43130638893235,"sku":"E-AB-16657-60","price":200.2,"currency_code":"CAD","in_stock":true},{"title":"120μL","offer_id":43130638926003,"sku":"E-AB-16657-120","price":336.0,"currency_code":"CAD","in_stock":true},{"title":"200μL","offer_id":43130638958771,"sku":"E-AB-16657-200","price":558.6,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_98d83a9f-1e7d-44d9-87ce-2e7b1c4133fe.png?v=1709810509","url":"https:\/\/afsbio.com\/products\/nphs2-polyclonal-antibody-e-ab-16657","provider":"AFSBio Inc.","version":"1.0","type":"link"}