{"product_id":"nqo1-monoclonal-antibody-bt-mca3158","title":"NQO1 Monoclonal Antibody - BT-MCA3158","description":"\u003cp\u003eNQO1 Monoclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Number: BT-MCA3158-50, BT-MCA3158-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: This gene is a member of the NAD(P)H dehydrogenase (quinone) family and encodes a cytoplasmic 2-electron reductase. This FAD-binding protein forms homodimers and reduces quinones to hydroquinones. This protein's enzymatic activity prevents the one electron reduction of quinones that results in the production of radical species. Mutations in this gene have been associated with tardive dyskinesia (TD), an increased risk of hematotoxicity after exposure to benzene, and susceptibility to various forms of cancer. Altered expression of this protein has been seen in many tumors and is also associated with Alzheimer's disease (AD). Alternate transcriptional splice variants, encoding different isoforms, have been characterized.\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Signal Transduction, Metabolism\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: NQO1\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, FCM\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human\u003c\/p\u003e\n\n\u003cp\u003eClonality: Monoclonal\u003c\/p\u003e\n\n\u003cp\u003eClone ID: 1A11\u003c\/p\u003e\n\n\u003cp\u003eHost: Mouse\u003c\/p\u003e\n\n\u003cp\u003eIsotype: Mouse IgG1\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: NQO1\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Purified recombinant fragment of human NQO1 expressed in E. Coli.\u003c\/p\u003e\n\n\u003cp\u003eStorage: 4°C|-20°C for long term storage\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Ascitic fluid containing 0.03% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight (Da): 31kDa\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: P15559\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: DTD, QR1, DHQU, DIA4, NMOR1, NMORI\u003c\/p\u003e\n\n\u003cp\u003eGeneID: 1728\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"50μL","offer_id":45238595289267,"sku":"BT-MCA3158-50","price":308.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45238595322035,"sku":"BT-MCA3158-100","price":448.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_7c0f351b-7df9-4431-bb71-f75b6df78504.png?v=1769382900","url":"https:\/\/afsbio.com\/products\/nqo1-monoclonal-antibody-bt-mca3158","provider":"AFSBio Inc.","version":"1.0","type":"link"}