{"product_id":"nqo1-polyclonal-antibody-e-ab-70139","title":"NQO1 Polyclonal Antibody - E-AB-70139","description":"\u003cp\u003eNQO1 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 60μL, 120μL, 200μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: E-AB-70139-60, E-AB-70139-120, E-AB-70139-200\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: NQO1\u003c\/p\u003e\n\n\u003cp\u003eTarget Synonym: Azoreductase; Cytochrome b 5 reductase; DHQU; DIA 4; DIA4; Diaphorase (NADH\/NADPH) (cytochrome b 5 reductase); Diaphorase (NADH\/NADPH); Diaphorase 4; Dioxin inducible 1; DT diaphorase; DT-diaphorase; DTD; Menadione reductase; NAD(P)H dehydrogenase [quinone] 1; NAD(P)H dehydrogenase quinone 1; NAD(P)H menadione oxidoreductase 1 dioxin inducible; NAD(P)H quinone dehydrogenase 1; NAD(P)H: menadione oxidoreductase 1 dioxin inducible 1; NAD(P)H:menadione oxidoreductase 1; NAD(P)H:Quinone acceptor oxidoreductase type 1; NAD(P)H:quinone oxidoreductase 1; NAD(P)H:quinone oxireductase; NMOR 1; NMOR I; NMOR1; NMORI; NQO 1; NQO1; NQO1; Phylloquinone reductase; QR 1; QR1; Quinone reductase 1\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Cancer, Metabolism, Signal Transduction\u003c\/p\u003e\n\n\u003cp\u003eConjugation: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eSpecies Reactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eApplication: WB\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n \n\n\u003cp\u003eUNIProt ID: P15559,P05982,Q64669\u003c\/p\u003e\n\n\u003cp\u003eBackground: This gene is a member of the NAD(P)H dehydrogenase (quinone) family and encodes a cytoplasmic 2-electron reductase. This FAD-binding protein forms homodimers and reduces quinones to hydroquinones. This protein's enzymatic activity prevents the one electron reduction of quinones that results in the production of radical species. Mutations in this gene have been associated with tardive dyskinesia (TD), an increased risk of hematotoxicity after exposure to benzene, and susceptibility to various forms of cancer. Altered expression of this protein has been seen in many tumors and is also associated with Alzheimer's disease (AD). Alternate transcriptional splice variants, encoding different isoforms, have been characterized.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 350 μg\/mL\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: KLH conjugated Synthetic peptide corresponding to Mouse NQO1\u003c\/p\u003e\n\n\u003cp\u003eBuffer: PBS with 0.02% sodium azide, 1% protective protein and 50% glycerol, pH7.4\u003c\/p\u003e\n\n\u003cp\u003ePurification Method: Affinity purification\u003c\/p\u003e\n\n\u003cp\u003eDilution: WB 1:500-1:1000\u003c\/p\u003e\n\n\u003cp\u003eCalculated MW: 31kDa\u003c\/p\u003e\n\n\u003cp\u003eObserved MW: 31kDa\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C\/One year. Avoid freeze \/ thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eShipping: Ice bag\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"60μL","offer_id":43146508468403,"sku":"E-AB-70139-60","price":224.0,"currency_code":"CAD","in_stock":true},{"title":"120μL","offer_id":43146508501171,"sku":"E-AB-70139-120","price":364.0,"currency_code":"CAD","in_stock":true},{"title":"200μL","offer_id":43146508533939,"sku":"E-AB-70139-200","price":574.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_501a1911-ec4a-4ef6-8d62-81af8e0798c3.png?v=1710296610","url":"https:\/\/afsbio.com\/products\/nqo1-polyclonal-antibody-e-ab-70139","provider":"AFSBio Inc.","version":"1.0","type":"link"}