{"product_id":"nr2c2-monoclonal-antibody-bt-mca2034","title":"NR2C2 Monoclonal Antibody - BT-MCA2034","description":"\u003cp\u003eNR2C2 Monoclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Number: BT-MCA2034-50, BT-MCA2034-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: This gene encodes a protein that belongs to the nuclear hormone receptor family. Members of this family act as ligand-activated transcription factors and function in many biological processes such as development, cellular differentiation and homeostasis. The activated receptor\/ligand complex is translocated to the nucleus where it binds to hormone response elements of target genes. The protein encoded by this gene plays a role in protecting cells from oxidative stress and damage induced by ionizing radiation. The lack of a similar gene in mouse results in growth retardation, severe spinal curvature, subfertility, premature aging, and prostatic intraepithelial neoplasia (PIN) development. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Apr 2014]\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Epigenetics and nuclear signaling\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: NR2C2\u003c\/p\u003e\n\n\u003cp\u003eApplications: FCM\u003c\/p\u003e\n\n\u003cp\u003eClonality: Monoclonal\u003c\/p\u003e\n\n\u003cp\u003eClone ID: 8H11D4\u003c\/p\u003e\n\n\u003cp\u003eHost: Mouse\u003c\/p\u003e\n\n\u003cp\u003eIsotype: Mouse IgG1\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: NR2C2\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Purified recombinant fragment of human NR2C2 (AA: 62-356) expressed in E. Coli.\u003c\/p\u003e\n\n\u003cp\u003eStorage: 4°C|-20°C for long term storage\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Purified antibody in PBS with 0.05% sodium azide\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight (Da): 65.4kDa\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: P49116\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: TR4, TAK1\u003c\/p\u003e\n\n\u003cp\u003eGeneID: 7182\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"50μL","offer_id":45238413525171,"sku":"BT-MCA2034-50","price":308.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45238413557939,"sku":"BT-MCA2034-100","price":448.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_9149f7ac-4016-4a88-bff9-3a9d016978a1.png?v=1769380322","url":"https:\/\/afsbio.com\/products\/nr2c2-monoclonal-antibody-bt-mca2034","provider":"AFSBio Inc.","version":"1.0","type":"link"}