{"product_id":"nr2c2-polyclonal-antibody-bt-ap12009","title":"NR2C2 Polyclonal Antibody - BT-AP12009","description":"\u003cp\u003eNR2C2 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BT-AP12009-20, BT-AP12009-50, BT-AP12009-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: This gene encodes a protein that belongs to the nuclear hormone receptor family. Members of this family act as ligand-activated transcription factors and function in many biological processes such as development, cellular differentiation and homeostasis. The activated receptor\/ligand complex is translocated to the nucleus where it binds to hormone response elements of target genes. The protein encoded by this gene plays a role in protecting cells from oxidative stress and damage induced by ionizing radiation. The lack of a similar gene in mouse results in growth retardation, severe spinal curvature, subfertility, premature aging, and prostatic intraepithelial neoplasia (PIN) development. Alternative splicing results in multiple transcript variants encoding different isoforms.\u003c\/p\u003e \n\n\u003cp\u003eResearch Areas: Epigenetics and nuclear signaling\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: NR2C2\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, ELISA\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: Nuclear receptor subfamily 2 group C member 2\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C for 1 year\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Human: P49116; Mouse: P49117; Rat: P55094\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: Nuclear receptor subfamily 2 group C member 2;Orphan nuclear receptor TAK1;Orphan nuclear receptor TR4;Testicular receptor 4\u003c\/p\u003e\n\n\u003cp\u003eGeneID: Human: 7182\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"20μL","offer_id":45239245340851,"sku":"BT-AP12009-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"50μL","offer_id":45239245373619,"sku":"BT-AP12009-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45239245406387,"sku":"BT-AP12009-100","price":385.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_34ae4a9f-a91c-4b3d-b4d7-4fe47ae96bad.png?v=1769391135","url":"https:\/\/afsbio.com\/products\/nr2c2-polyclonal-antibody-bt-ap12009","provider":"AFSBio Inc.","version":"1.0","type":"link"}