{"product_id":"nrbp-rabbit-pab-es10837","title":"NRBP rabbit pAb - ES10837","description":"\u003cp\u003eNRBP rabbit pAb\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: ES10837-50, ES10837-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: caution:Author states that kinase activity observed in PubMed:11956649 may be due to sample contamination. This protein is predicted to be catalytically inactive., domain:The protein kinase domain is predicted to be catalytically inactive., function:May play a role in subcellular trafficking between the endoplasmic reticulum and Golgi apparatus through interactions with the Rho-type GTPases. Binding to the NS3 protein of dengue virus type 2 appears to subvert this activity into the alteration of the intracellular membrane structure associated with flaviviral replication., similarity:Belongs to the protein kinase superfamily. Ser\/Thr protein kinase family., similarity:Contains 1 protein kinase domain., subcellular location:Colocalizes with activated RAC3 to endomembranes and at the cell periphery in lamellipodia., subunit:Homodimer. Binds to MLF1, recruiting a serine kinase which phosphorylates both itself and MLF1. Phosphorylated MLF1 binds to YWHAZ and is retained in the cytoplasm., tissue specificity:Ubiquitously expressed in all tissues examined with high levels in the testis.,\u003c\/p\u003e \n\n\u003cp\u003eSource: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB; ELISA\u003c\/p\u003e\n\n\u003cp\u003eDilution: WB 1:500-2000 ELISA 1:5000-20000\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human; Mouse\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Synthesized peptide derived from part region of human protein\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: -20°C\/1 year\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eObserved Band (KD): 58kD\u003c\/p\u003e\n\n\u003cp\u003eHuman Gene ID: 29959\u003c\/p\u003e\n\n\u003cp\u003eHuman SWISS Prot NO: Q9UHY1\u003c\/p\u003e\n\n\u003cp\u003eSubcellular Location: Cytoplasm, cell cortex. Endomembrane system. Cell projection, lamellipodium. Colocalizes with activated RAC3 to endomembranes and at the cell periphery in lamellipodia.\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"ELK Bio","offers":[{"title":"50μL","offer_id":45201738662067,"sku":"ES10837-50","price":207.2,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45201738694835,"sku":"ES10837-100","price":347.2,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/download_360x_d7104b05-b28c-4081-b4b7-912f39197f9e.png?v=1767110684","url":"https:\/\/afsbio.com\/products\/nrbp-rabbit-pab-es10837","provider":"AFSBio Inc.","version":"1.0","type":"link"}