{"product_id":"nrg1-polyclonal-antibody-bs6037","title":"NRG1 Polyclonal Antibody-BS6037","description":"\u003cp\u003eNRG1 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50µl, 100µl\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BS6037-50, BS6037-100\u003c\/p\u003e\n\n\u003cp\u003eProduct: Rabbit IgG, 1mg\/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2\u003c\/p\u003e\n\n\u003cp\u003eSwiss-Prot: Q02297\u003c\/p\u003e \n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, IHC, IF\u003c\/p\u003e\n\n\u003cp\u003eAll Applications: WB 1:500 - 1:2000\u003cbr\u003e\nIHC 1:50 - 1:100\u003cbr\u003e\nIF 1:50 - 1:100\u003c\/p\u003e\n\n\u003cp\u003eBackground: Neuregulin-1 gene, NRG1, encodes numerous splice variants with differing transcription initiation sites. Neuregulin-1 includes a range of isoforms with varying glycosylation, regulation of expression and function. Neuregulin-1 splice variants each bear an EGF-like domain, though otherwise have unique domain structures, differing functions and discrete tissue distribution. Six types of Neuregulin-1 isoform groups have been defined based on their structural features. Three types are most often described, type I (ARIA, NDF or HRG), type II (GGF) and type III (SMDF). Neuregulin-1 has been linked to schizophrenia and has diverse neural functions. Neuregulin-1 affects cell migration, the differentiation of neural crest and Schwann cells, and acts to upregulate the expression of acetylcholine receptors at muscle fibers during the formation of neuromuscular junctions.\u003c\/p\u003e\n\n\u003cp\u003ePurification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is \u0026gt; 95% (by SDS-PAGE).\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eSpecificity: NRG1 polyclonal antibody detects endogenous levels of NRG1 protein.\u003c\/p\u003e\n\n\u003cp\u003eBioworld Molecular Weight: ~ 70 kDa\u003c\/p\u003e\n\n\u003cp\u003eNote: For research use only, not for use in diagnostic procedure.\u003c\/p\u003e\n\n\u003cp\u003eExtra Notes: Western Blot (WB) analysis of NRG1 polyclonal antibody.\u003c\/p\u003e\n\n\u003cp\u003eAlternative Name: Acetylcholine receptor inducing activity; \u003cbr\u003e\nAcetylcholine receptor-inducing activity; \u003cbr\u003e\nARIA; \u003cbr\u003e\nBreast cancer cell differentiation factor p45; \u003cbr\u003e\nERBB2 p185 activator; \u003cbr\u003e\nGGF 2; \u003cbr\u003e\nGGF; \u003cbr\u003e\nGGF2; \u003cbr\u003e\nGlial growth factor; \u003cbr\u003e\nHeregulin alpha; \u003cbr\u003e\nHeregulin; \u003cbr\u003e\nheregulin; alpha (45; ERBB2 p185-activator); \u003cbr\u003e\nHGL; \u003cbr\u003e\nHRG 1; \u003cbr\u003e\nHRG; \u003cbr\u003e\nHRG1; \u003cbr\u003e\nHRGA; \u003cbr\u003e\nMST131; \u003cbr\u003e\nNDF; \u003cbr\u003e\nNeu differentiation factor; \u003cbr\u003e\nNeuregulin 1; \u003cbr\u003e\nneuregulin 1 type IV beta 1a; \u003cbr\u003e\nneuregulin 1 type IV beta 3; \u003cbr\u003e\nNeuregulin-1; \u003cbr\u003e\nNeuregulin1; \u003cbr\u003e\nNRG 1; \u003cbr\u003e\nnrg1; \u003cbr\u003e\nNRG1; \u003cbr\u003e\nOTTHU\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Recombinant full length Human NRG1.\u003c\/p\u003e\n\n\u003cp\u003eConjugate: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eModification: Unmodified\u003c\/p\u003e","brand":"BioWorld","offers":[{"title":"50µl","offer_id":42923465375923,"sku":"BS6037-50","price":342.59,"currency_code":"CAD","in_stock":true},{"title":"100µl","offer_id":42923465408691,"sku":"BS6037-100","price":589.65,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/thumbnail_d1447bac803ec9be_11-14-09-19-51_e49d9452-37dc-4f7b-8990-016ce537daea.jpg?v=1703850009","url":"https:\/\/afsbio.com\/products\/nrg1-polyclonal-antibody-bs6037","provider":"AFSBio Inc.","version":"1.0","type":"link"}