{"product_id":"nrgn-polyclonal-antibody-e-ab-62847","title":"NRGN Polyclonal Antibody - E-AB-62847","description":"\u003cp\u003eNRGN Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 60μL, 120μL, 200μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: E-AB-62847-60, E-AB-62847-120, E-AB-62847-200\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: NRGN\u003c\/p\u003e\n\n\u003cp\u003eTarget Synonym: NRGN; RC3; hng\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Cancer, Neuroscience\u003c\/p\u003e\n\n\u003cp\u003eConjugation: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eSpecies Reactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eApplication: WB\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n \n\n\u003cp\u003eUNIProt ID: Q92686\u003c\/p\u003e\n\n\u003cp\u003eBackground: Neurogranin (NRGN) is the human homolog of the neuron-specific rat RC3\/neurogranin gene. This gene encodes a postsynaptic protein kinase substrate that binds calmodulin in the absence of calcium. The NRGN gene contains four exons and three introns. The exons 1 and 2 encode the protein and exons 3 and 4 contain untranslated sequences. It is suggested that the NRGN is a direct target for thyroid hormone in human brain, and that control of expression of this gene could underlay many of the consequences of hypothyroidism on mental states during development as well as in adult subjects.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1mg\/mL\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Recombinant fusion protein of human NRGN (NP_001119653.1).\u003c\/p\u003e\n\n\u003cp\u003eBuffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.\u003c\/p\u003e\n\n\u003cp\u003ePurification Method: Affinity purification\u003c\/p\u003e\n\n\u003cp\u003eDilution: WB \t1:500-1:2000\u003c\/p\u003e\n\n\u003cp\u003eCalculated MW: 7kDa\u003c\/p\u003e\n\n\u003cp\u003eObserved MW: 14kDa\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C\/One year. Avoid freeze \/ thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eShipping: Ice bag\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"60μL","offer_id":43146265166003,"sku":"E-AB-62847-60","price":280.0,"currency_code":"CAD","in_stock":true},{"title":"120μL","offer_id":43146265198771,"sku":"E-AB-62847-120","price":448.0,"currency_code":"CAD","in_stock":true},{"title":"200μL","offer_id":43146265231539,"sku":"E-AB-62847-200","price":742.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_b010cc68-beef-46a8-9936-4ec0c1349bc8.png?v=1710292635","url":"https:\/\/afsbio.com\/products\/nrgn-polyclonal-antibody-e-ab-62847","provider":"AFSBio Inc.","version":"1.0","type":"link"}