{"product_id":"ntrk1-polyclonal-antibody-e-ab-66502","title":"NTRK1 Polyclonal Antibody - E-AB-66502","description":"\u003cp\u003eNTRK1 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 60μL, 120μL, 200μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: E-AB-66502-60, E-AB-66502-120, E-AB-66502-200\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: NTRK1\u003c\/p\u003e\n\n\u003cp\u003eTarget Synonym: NTRK1; MTC; TRK; TRK1; TRKA; Trk-A; p140-TrkA\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Cancer, Neuroscience\u003c\/p\u003e\n\n\u003cp\u003eConjugation: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eSpecies Reactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eApplication: WB, IHC\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n \n\n\u003cp\u003eUNIProt ID: P04629\u003c\/p\u003e\n\n\u003cp\u003eBackground: This gene encodes a member of the neurotrophic tyrosine kinase receptor (NTKR) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. The presence of this kinase leads to cell differentiation and may play a role in specifying sensory neuron subtypes. Mutations in this gene have been associated with congenital insensitivity to pain, anhidrosis, self-mutilating behavior, mental retardation and cancer. Alternate transcriptional splice variants of this gene have been found, but only three have been characterized to date.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1mg\/mL\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: A synthetic peptide of human NTRK1 (NP_002520.2).\u003c\/p\u003e\n\n\u003cp\u003eBuffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.\u003c\/p\u003e\n\n\u003cp\u003ePurification Method: Affinity purification\u003c\/p\u003e\n\n\u003cp\u003eDilution: WB \t1:500-1:2000   IHC \t1:50-1:200\u003c\/p\u003e\n\n\u003cp\u003eCalculated MW: 77kDa\/83kDa\/86kDa\/87kDa\u003c\/p\u003e\n\n\u003cp\u003eObserved MW: 140kDa\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C\/One year. Avoid freeze \/ thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eShipping: Ice bag\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"60μL","offer_id":43146419241139,"sku":"E-AB-66502-60","price":280.0,"currency_code":"CAD","in_stock":true},{"title":"120μL","offer_id":43146419273907,"sku":"E-AB-66502-120","price":448.0,"currency_code":"CAD","in_stock":true},{"title":"200μL","offer_id":43146419306675,"sku":"E-AB-66502-200","price":742.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_00036ed4-4b9f-4b6f-89db-bba4a123ffdd.png?v=1710295227","url":"https:\/\/afsbio.com\/products\/ntrk1-polyclonal-antibody-e-ab-66502","provider":"AFSBio Inc.","version":"1.0","type":"link"}