{"product_id":"ntrk3-monoclonal-antibody-bt-mca4136","title":"NTRK3 Monoclonal Antibody - BT-MCA4136","description":"\u003cp\u003eNTRK3 Monoclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Number: BT-MCA4136-50, BT-MCA4136-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: NTRK3 (neurotrophic tyrosine kinase, receptor, type 3), it is a member of the neurotrophic tyrosine receptor kinase (NTRK) family and plays an important role in the development and maintenance of neural tissues. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. Signalling through this kinase leads to cell differentiation and may play a role in the development of proprioceptive neurons that sense body position. Mutations in this gene have been associated with medulloblastomas, secretory breast carcinomas and other cancers.\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Neuroscience\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: NTRK3\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human\u003c\/p\u003e\n\n\u003cp\u003eClonality: Monoclonal\u003c\/p\u003e\n\n\u003cp\u003eClone ID: 4G5\u003c\/p\u003e\n\n\u003cp\u003eHost: Mouse\u003c\/p\u003e\n\n\u003cp\u003eIsotype: Mouse IgG1\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: NTRK3\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Purified recombinant extracellular fragment of human NTRK3 (aa32-429) fused with hIgGFc tag expressed in HEK293 cells.\u003c\/p\u003e\n\n\u003cp\u003eStorage: 4°C|-20°C for long term storage\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Ascitic fluid containing 0.03% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight (Da): 94kDa\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Q16288\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: TRKC, gp145(trkC)\u003c\/p\u003e\n\n\u003cp\u003eGeneID: 4916\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"50μL","offer_id":45238427320499,"sku":"BT-MCA4136-50","price":308.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45238427353267,"sku":"BT-MCA4136-100","price":448.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_a05d1e10-8ee1-4368-9c9b-a922df184bfb.png?v=1769380631","url":"https:\/\/afsbio.com\/products\/ntrk3-monoclonal-antibody-bt-mca4136","provider":"AFSBio Inc.","version":"1.0","type":"link"}