{"product_id":"numa-polyclonal-antibody-bt-ap06231","title":"NuMA Polyclonal Antibody - BT-AP06231","description":"\u003cp\u003eNuMA Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BT-AP06231-20, BT-AP06231-50, BT-AP06231-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: NUMA1 encodes a large protein that forms a structural component of the nuclear matrix. The encoded protein interacts with microtubules and plays a role in the formation and organization of the mitotic spindle during cell division. Chromosomal translocation of NUMA1 with the RARA (retinoic acid receptor, alpha) gene on chromosome 17 have been detected in patients with acute promyelocytic leukemia. Alternative splicing results in multiple transcript variants.\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Cell Biology\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: NUMA1\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, IHC-p, ELISA\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: NuMA Antibody\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C for 1 year\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight (Da): 238260\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Human: Q14980\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: NUMA1; NUMA; Nuclear mitotic apparatus protein 1; NuMA protein; SP-H antigen\u003c\/p\u003e\n\n\u003cp\u003eGeneID: Human: 4926\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"20μL","offer_id":45239760355507,"sku":"BT-AP06231-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"50μL","offer_id":45239760388275,"sku":"BT-AP06231-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45239760421043,"sku":"BT-AP06231-100","price":385.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_f9c3c3c6-35d4-4aeb-9474-ad35e65d12cf.png?v=1769398919","url":"https:\/\/afsbio.com\/products\/numa-polyclonal-antibody-bt-ap06231","provider":"AFSBio Inc.","version":"1.0","type":"link"}