{"product_id":"oas2-polyclonal-antibody-bt-ap06309","title":"OAS2 Polyclonal Antibody - BT-AP06309","description":"\u003cp\u003eOAS2 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BT-AP06309-20, BT-AP06309-50, BT-AP06309-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: OAS2 encodes a member of the 2-5A synthetase family, essential proteins involved in the innate immune response to viral infection. The 2'-5'-oligoadenylate synthetase 2 is induced by interferons and uses adenosine triphosphate in 2'-specific nucleotidyl transfer reactions to synthesize 2',5'-oligoadenylates (2-5As). These molecules activate latent RNase L, which results in viral RNA degradation and the inhibition of viral replication. The three known members of this gene family are located in a cluster on chromosome 12. Alternatively spliced transcript variants encoding different isoforms have been described.\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Immunology\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: OAS2\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, IHC-p, ELISA\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: OAS2 Antibody\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C for 1 year\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight (Da): 82431\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Human: P29728; Mouse: E9Q9A9; Rat: Q5MYU0\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: OAS2; 2'-5'-oligoadenylate synthase 2; (2-5')oligo(A) synthase 2; 2-5A synthase 2; p69 OAS \/ p71 OAS; p69OAS \/ p71OAS\u003c\/p\u003e\n\n\u003cp\u003eGeneID: Human: 4939; Mouse: 246728; Rat: 363938\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"20μL","offer_id":45239763861683,"sku":"BT-AP06309-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"50μL","offer_id":45239763894451,"sku":"BT-AP06309-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45239763927219,"sku":"BT-AP06309-100","price":385.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_b06751e8-9216-4597-bd14-d723162596a6.png?v=1769398940","url":"https:\/\/afsbio.com\/products\/oas2-polyclonal-antibody-bt-ap06309","provider":"AFSBio Inc.","version":"1.0","type":"link"}