{"product_id":"ob-r-phospho-tyr1141-polyclonal-antibody-ra28002","title":"Ob-R (phospho Tyr1141) Polyclonal Antibody - RA28002","description":"\u003cp\u003eOb-R (phospho Tyr1141) Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: RA28002-50, RA28002-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: leptin receptor (LEPR) Homo sapiens The protein encoded by this gene belongs to the gp130 family of cytokine receptors that are known to stimulate gene transcription via activation of cytosolic STAT proteins. This protein is a receptor for leptin (an adipocyte-specific hormone that regulates body weight), and is involved in the regulation of fat metabolism, as well as in a novel hematopoietic pathway that is required for normal lymphopoiesis. Mutations in this gene have been associated with obesity and pituitary dysfunction. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. It is noteworthy that this gene and LEPROT gene (GeneID:54741) share the same promoter and the first 2 exons, however, encode distinct proteins (PMID:9207021) .[provided by RefSeq, Nov 2010],\u003c\/p\u003e\n\n\u003cp\u003eCondition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eStorage Instructions: -20°C\/1 year\u003c\/p\u003e\n\n\u003cp\u003eRecommended dilutions: Western Blot: 1\/500 - 1\/2000. ELISA: 1\/5000. Not yet tested in other applications.\u003c\/p\u003e\n\n\u003cp\u003eAlternative Names: LEPR; DB; OBR; Leptin receptor; LEP-R; HuB219; OB receptor; OB-R; CD antigen CD295\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB; ELISA\u003c\/p\u003e\n\n\u003cp\u003eSpecies Cross-Reactivity: Human; Mouse\u003c\/p\u003e\n\n\u003cp\u003eGeneID (Human): 3953\u003c\/p\u003e\n\n\u003cp\u003eProtein MW (KDa): 132\u003c\/p\u003e\n\n\u003cp\u003eSWISS: P48357\u003c\/p\u003e\n\n\u003cp\u003eSource: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Reed Bio","offers":[{"title":"50μL","offer_id":45121432846515,"sku":"RA28002-50","price":336.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45121432879283,"sku":"RA28002-100","price":448.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_84858c07-ca65-4b47-9882-9e09a2a4b1f2.png?v=1773347600","url":"https:\/\/afsbio.com\/products\/ob-r-phospho-tyr1141-polyclonal-antibody-ra28002","provider":"AFSBio Inc.","version":"1.0","type":"link"}