{"product_id":"ocln-rabbit-pab-es11811","title":"OCLN rabbit pAb - ES11811","description":"\u003cp\u003eOCLN rabbit pAb\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: ES11811-50, ES11811-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: This gene encodes an integral membrane protein that is required for cytokine-induced regulation of the tight junction paracellular permeability barrier. Mutations in this gene are thought to be a cause of band-like calcification with simplified gyration and polymicrogyria (BLC-PMG), an autosomal recessive neurologic disorder that is also known as pseudo-TORCH syndrome. Alternative splicing results in multiple transcript variants. A related pseudogene is present 1.5 Mb downstream on the q arm of chromosome 5. [provided by RefSeq, Apr 2011],\u003c\/p\u003e \n\n\u003cp\u003eSource: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB IF; ELISA\u003c\/p\u003e\n\n\u003cp\u003eDilution: WB 1:500-2000 IF 1:100-300 ELISA 1:5000-20000 Not yet tested in other applications.\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human; Mouse; Rat\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Synthesized peptide derived from part region of human protein. AA350-400\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: -20°C\/1 year\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eObserved Band (KD): 57kD\u003c\/p\u003e\n\n\u003cp\u003eHuman Gene ID: 100506658\u003c\/p\u003e\n\n\u003cp\u003eHuman SWISS Prot NO: Q16625\u003c\/p\u003e\n\n\u003cp\u003eSubcellular Location: Cell membrane; Multi-pass membrane protein. Cell junction, tight junction.\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"ELK Bio","offers":[{"title":"50μL","offer_id":45201778671795,"sku":"ES11811-50","price":207.2,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45201778704563,"sku":"ES11811-100","price":347.2,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/download_360x_cf0c72ef-5e9b-45ec-b40f-94a262536804.png?v=1767111600","url":"https:\/\/afsbio.com\/products\/ocln-rabbit-pab-es11811","provider":"AFSBio Inc.","version":"1.0","type":"link"}