{"product_id":"ocrl-polyclonal-antibody-bt-ap06327","title":"OCRL Polyclonal Antibody - BT-AP06327","description":"\u003cp\u003eOCRL Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BT-AP06327-20, BT-AP06327-50, BT-AP06327-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: OCRL encodes an inositol polyphosphate 5-phosphatase. OCRL, inositol polyphosphate-5-phosphatase is involved in regulating membrane trafficking and is located in numerous subcellular locations including the trans-Golgi network, clathrin-coated vesicles and, endosomes and the plasma membrane. OCRL, inositol polyphosphate-5-phosphatase may also play a role in primary cilium formation. Mutations in OCRL cause oculocerebrorenal syndrome of Lowe and also Dent disease. Alternate splicing results in multiple transcript variants.\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Signal Transduction\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: OCRL\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, ELISA\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: OCRL Antibody\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C for 1 year\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight (Da): 104205\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Human: Q01968\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: OCRL; INPP5F; OCRL1; Inositol polyphosphate 5-phosphatase OCRL-1; Lowe oculocerebrorenal syndrome protein\u003c\/p\u003e\n\n\u003cp\u003eGeneID: Human: 4952\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"20μL","offer_id":45239764746419,"sku":"BT-AP06327-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"50μL","offer_id":45239764779187,"sku":"BT-AP06327-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45239764811955,"sku":"BT-AP06327-100","price":385.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_8663bb2c-bdec-46b5-8c93-1d5824d618e2.png?v=1769398954","url":"https:\/\/afsbio.com\/products\/ocrl-polyclonal-antibody-bt-ap06327","provider":"AFSBio Inc.","version":"1.0","type":"link"}