CALIXAR’s ODG reagent is a non-ionic amphiphilic detergent / surfactant with a diglucose polar group and an octyl chain.
Compound name: ODG
Catalogue number: ODG_100MG, ODG_250MG
Molec. Formula: C27H51NO13S
MW: 629.8 g/mol
Percent Composition: C, 51.49; H, 8.16; N, 2.22; O, 33.03; S, 5.09
Physical state: White powder
Purity (HPLC, 214nm): ≥95%
Retention time (RP18 HPLC)b: tR = 12.9 min
CMC: >10 mM
Exact mass: 629.3081
Stability: Store in <-20°C freezer for up to one year
Solubility Structure: Soluble in water (0.5M), methanol and DMSO.
CALIXAR uses a novel & tailored approach
Clients are able to use ODG to help produce lipid detergents, mixed micelles, and protein detergent micelles. ODG allows clients to extract, to solubilize and to stabilize native and functional membrane proteins in solution.
CALIXAR’s ODG is very mild detergent to extract, to solubilize and to stabilize native membrane proteins and is non-ionic. Accordingly, it is not sensitive to ionic concentration or pH fluctuations which is excellent to extract, to solubilize and to stabilize specific membrane proteins.
ODG can extract, solubilize and stabilize more efficiently delicate membrane proteins of high medical relevance.
Native Full-Length Proteins
CALIXAR’s ODG is non-ionic and therefore is not receptive to ionic strength or pH variations and could be well adapted to extract, to solubilize and to stabilize specific membrane proteins.
Specially Made for Biotech
CLAIXAR’s ODG extract high-quality membrane proteins used for research, drug discovery including structural studies and are adapted for use in pharmaceutical, biotechnology companies, as well as for academic teams (biochemists, structural biologists, pharmacologists, virologists) that are involved in the life science fields.
For Any Life Science Project
- Antibodies (including nanobodies, scaffold proteins, aptamers)
- Small molecules
- 3D Structures (cryoEM, XRay crystallography, NMR, SANS, SAXS)
- Drug discovery (Screening: HTS, FBDD, SBDD; Hit and lead validation)
- Antibody discovery (Immunization and display technologies)
- Clinical stage
Lactobionamide Surfactants with Hydrogenated, Perfluorinated or Hemifluorinated Tails
Lebaupain F. et al. 2006