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ODG Reagent

ODG Reagent

$220.69 USD
$220.69 USD
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CALIXAR’s ODG reagent is a non-ionic amphiphilic detergent / surfactant with a diglucose polar group and an octyl chain.

 

N-(2-methyl-1,3-bis(O-β-D-Glucose)propan-2-yl)-3-(octylthio)propanamide

​ 

Compound name: ODG

Catalogue number: ODG_100MG, ODG_250MG

Molec. Formula: C27H51NO13S

CAS: nd

MW: 629.8 g/mol

pKa: na​

Percent Composition: C, 51.49; H, 8.16; N, 2.22; O, 33.03; S, 5.09

Physical state: White powder

Purity (HPLC, 214nm): ≥95%

Retention time (RP18 HPLC)b: tR = 12.9 min

CMC: >10 mM

Exact mass​: 629.3081

Stability: Store in <-20°C freezer for up to one year

Solubility Structure: Soluble in water (0.5M), methanol and DMSO.

 

pDF symbolDATASHEET

 

CALIXAR uses a novel & tailored approach 

CALIXAR’s ODG is manufactured in a powder form and is used in aqueous solution or buffer. ODG can be processed with biological materials (biological membranes).

Clients are able to use ODG to help produce lipid detergents, mixed micelles, and protein detergent micelles. ODG allows clients to extract, to solubilize and to stabilize native and functional membrane proteins in solution.

CALIXAR’s ODG is very mild detergent to extract, to solubilize and to stabilize native membrane proteins and is non-ionic. Accordingly, it is not sensitive to ionic concentration or pH fluctuations which is excellent to extract, to solubilize and to stabilize specific membrane proteins.

ODG can extract, solubilize and stabilize more efficiently delicate membrane proteins of high medical relevance.

 

CALIXAR’s ODG is non-ionic and therefore is not receptive to ionic strength or pH variations and could be well adapted to extract, to solubilize and to stabilize specific membrane proteins.

 

CLAIXAR’s ODG extract high-quality membrane proteins used for research, drug discovery including structural studies and are adapted for use in pharmaceutical, biotechnology companies, as well as for academic teams (biochemists, structural biologists, pharmacologists, virologists) that are involved in the life science fields.

 

  • Antibodies (including nanobodies, scaffold proteins, aptamers)
  • Small molecules
  • 3D Structures (cryoEM, XRay crystallography, NMR, SANS, SAXS)
  • Drug discovery (Screening: HTS, FBDD, SBDD; Hit and lead validation)
  • Antibody discovery (Immunization and display technologies)
  • Clinical stage

References

ACS PUBLICATIONS

Lactobionamide Surfactants with Hydrogenated, Perfluorinated or Hemifluorinated Tails

Lebaupain F. et al. 2006

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