{"product_id":"opa1-polyclonal-antibody-bt-ap12421","title":"OPA1 Polyclonal Antibody - BT-AP12421","description":"\u003cp\u003eOPA1 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BT-AP12421-20, BT-AP12421-50, BT-AP12421-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: This gene product is a nuclear-encoded mitochondrial protein with similarity to dynamin-related GTPases. It is a component of the mitochondrial network. Mutations in this gene have been associated with optic atrophy type 1, which is a dominantly inherited optic neuropathy resulting in progressive loss of visual acuity, leading in many cases to legal blindness. Multiple transcript variants encoding different isoforms have been found for this gene.\u003c\/p\u003e \n\n\u003cp\u003eResearch Areas: Cardiovascular; Metabolism; Neuroscience\u003c\/p\u003e \n\n\u003cp\u003eTarget Protein: OPA1\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, ELISA\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: Dynamin-like 120 kDa protein, mitochondrial\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C for 1 year\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Human: O60313; Mouse: P58281; Rat: Q2TA68\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: Dynamin-like 120 kDa protein, mitochondrial;Optic atrophy protein 1 [Cleaved into: Dynamin-like 120 kDa protein, form S1]\u003c\/p\u003e\n\n\u003cp\u003eGeneID: Human: 4976\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"20μL","offer_id":45239258775731,"sku":"BT-AP12421-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"50μL","offer_id":45239258808499,"sku":"BT-AP12421-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45239258841267,"sku":"BT-AP12421-100","price":385.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_d17b5059-1f45-4729-ad08-54f28e4ca4b7.png?v=1769392146","url":"https:\/\/afsbio.com\/products\/opa1-polyclonal-antibody-bt-ap12421","provider":"AFSBio Inc.","version":"1.0","type":"link"}