{"product_id":"opg-monoclonal-antibody-bt-mca0960","title":"OPG Monoclonal Antibody - BT-MCA0960","description":"\u003cp\u003eOPG Monoclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Number: BT-MCA0960-50, BT-MCA0960-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: The protein encoded by this gene is a member of the TNF-receptor superfamily. This protein is an osteoblast-secreted decoy receptor that functions as a negative regulator of bone resorption. This protein specifically binds to its ligand, osteoprotegerin ligand, both of which are key extracellular regulators of osteoclast development. Studies of the mouse counterpart also suggest that this protein and its ligand play a role in lymph-node organogenesis and vascular calcification. Alternatively spliced transcript variants of this gene have been reported, but their full length nature has not been determined.\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Cardiovascular; Signal transduction; Metabolism; Developmental biology; Immunology\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: TNFRSF11B\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, IF, ICC, FCM, ELISA\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human\u003c\/p\u003e\n\n\u003cp\u003eClonality: Monoclonal\u003c\/p\u003e\n\n\u003cp\u003eHost: Mouse\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: Tumor necrosis factor receptor superfamily member 11B\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C for 1 year\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Human: O00300; Mouse: O08712\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: TNFRSF11B; OCIF; OPG; Tumor necrosis factor receptor superfamily member 11B; Osteoclastogenesis inhibitory factor; Osteoprotegerin\u003c\/p\u003e\n\n\u003cp\u003eGeneID: Human: 4982\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"50μL","offer_id":45238737961139,"sku":"BT-MCA0960-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45238737993907,"sku":"BT-MCA0960-100","price":420.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_e332d85c-1863-439e-8894-e76aea9a1f7d.png?v=1769384260","url":"https:\/\/afsbio.com\/products\/opg-monoclonal-antibody-bt-mca0960","provider":"AFSBio Inc.","version":"1.0","type":"link"}