{"product_id":"oscar-polyclonal-antibody-bt-ap12553","title":"OSCAR Polyclonal Antibody - BT-AP12553","description":"\u003cp\u003eOSCAR Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BT-AP12553-20, BT-AP12553-50, BT-AP12553-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: Osteoclasts are multinucleated cells that resorb bone and are essential for bone homeostasis. This gene encodes an osteoclast-associated receptor (OSCAR), which is a member of the leukocyte receptor complex protein family that plays critical roles in the regulation of both innate and adaptive immune responses. The encoded protein may play a role in oxidative stress-mediated atherogenesis as well as monocyte adhesion. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.\u003c\/p\u003e \n\n\u003cp\u003eResearch Areas: Immunology; Signal transduction; Tags and cell markers\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: OSCAR\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, ELISA\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: Osteoclast-associated immunoglobulin-like receptor\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C for 1 year\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Human: Q8IYS5; Mouse: Q8VBT3\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: Osteoclast-associated immunoglobulin-like receptor;Osteoclast-associated receptor;hOSCAR;Polymeric immunoglobulin receptor 3;PIgR-3;PIgR3;Poly-Ig receptor 3\u003c\/p\u003e\n\n\u003cp\u003eGeneID: Human: 126014\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"20μL","offer_id":45239272145075,"sku":"BT-AP12553-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"50μL","offer_id":45239272177843,"sku":"BT-AP12553-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45239272210611,"sku":"BT-AP12553-100","price":385.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_c81279d4-ff17-4cba-be1a-d4863eb648aa.png?v=1769392335","url":"https:\/\/afsbio.com\/products\/oscar-polyclonal-antibody-bt-ap12553","provider":"AFSBio Inc.","version":"1.0","type":"link"}