{"product_id":"osire1-rabbit-pab-a20585","title":"OsIRE1 Rabbit pAb - A20585","description":"\u003cp\u003eOsIRE1 Rabbit pAb\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: A20585-20, A20585-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: Involved in endoplasmic reticulum (ER) stress response. Senses unfolded proteins in the lumen of the ER via its N-terminal domain which leads to enzyme auto-activation. The active endoribonuclease domain splices bZIP50 mRNA to generate a new C-terminus, converting it into a potent unfolded-protein response (UPR) transcriptional activator, which then induces transcription of UPR target genes, such as luminal-binding protein (BiP) chaperones.\u003c\/p\u003e\n\n\u003cp\u003eCategory: Polyclonal Antibodies\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, ELISA\u003c\/p\u003e\n\n\u003cp\u003eCross-reactivity: Oryza sativa\u003c\/p\u003e\n\n\u003cp\u003eProtein Weight: 99kDa\u003c\/p\u003e\n\n\u003cp\u003eObserved Molecular Weight: 90kDa\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Recombinant protein (or fragment)\u003c\/p\u003e\n\n\u003cp\u003eSpecies: Oryza sativa\u003c\/p\u003e\n\n\u003cp\u003eGeneID: 4343198\u003c\/p\u003e\n\n\u003cp\u003eSWISS: Q7XIT1\u003c\/p\u003e\n\n\u003cp\u003eAlternate Names: IRE1; OsIRE1; OsIre1p; OsJ_24190; OJ1103_E04.109\u003c\/p\u003e\n\n\u003cp\u003eSource: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003ePurity: Affinity purification\u003c\/p\u003e\n\n\u003cp\u003eStorage: Store at -20℃. Avoid freeze \/ thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.\u003c\/p\u003e\n\n\u003cp\u003eRecommended Dilutions: WB, 1:500 - 1:2000 ELISA, Recommended starting concentration is 1 μg\/mL. Please optimize the concentration based on your specific assay requirements.\u003c\/p\u003e\n\n\u003cp\u003eNCBI Alias: LOC4343198\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"ABclonal","offers":[{"title":"20uL","offer_id":45189400133811,"sku":"A20585-20","price":207.2,"currency_code":"CAD","in_stock":true},{"title":"100uL","offer_id":45189400166579,"sku":"A20585-100","price":515.2,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/download_58c8d3c6-42d3-4deb-a895-04bba82a3b8c.png?v=1766426313","url":"https:\/\/afsbio.com\/products\/osire1-rabbit-pab-a20585","provider":"AFSBio Inc.","version":"1.0","type":"link"}