{"product_id":"osm-polyclonal-antibody-bt-ap12554","title":"OSM Polyclonal Antibody - BT-AP12554","description":"\u003cp\u003eOSM Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BT-AP12554-20, BT-AP12554-50, BT-AP12554-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: This gene encodes a member of the leukemia inhibitory factor\/oncostatin-M (LIF\/OSM) family of proteins. The encoded preproprotein is proteolytically processed to generate the mature protein. This protein is a secreted cytokine and growth regulator that inhibits the proliferation of a number of tumor cell lines. This protein also regulates the production of other cytokines, including interleukin 6, granulocyte-colony stimulating factor and granulocyte-macrophage colony stimulating factor in endothelial cells. This gene and the related gene, leukemia inhibitory factor, also present on chromosome 22, may have resulted from the duplication of a common ancestral gene. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed.\u003c\/p\u003e \n\n\u003cp\u003eResearch Areas: Cardiovascular; Immunology\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: OSM\u003c\/p\u003e\n\n\u003cp\u003eApplications: IHC-p, IF, ELISA\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Rat, Mouse\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: Oncostatin-M\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C for 1 year\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Human: P13725; Mouse: P53347\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: Oncostatin-M;OSM; Oncostatin-M; OSM\u003c\/p\u003e\n\n\u003cp\u003eGeneID: Human: 5008; Mouse: 18413\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"20μL","offer_id":45239272243379,"sku":"BT-AP12554-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"50μL","offer_id":45239272276147,"sku":"BT-AP12554-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45239272308915,"sku":"BT-AP12554-100","price":385.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_89451468-f5ec-4ad2-ad92-6d9a1b0ee162.png?v=1769392337","url":"https:\/\/afsbio.com\/products\/osm-polyclonal-antibody-bt-ap12554","provider":"AFSBio Inc.","version":"1.0","type":"link"}