{"product_id":"osm-polyclonal-antibody-e-ab-62158","title":"OSM Polyclonal Antibody - E-AB-62158","description":"\u003cp\u003eOSM Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 60μL, 120μL, 200μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: E-AB-62158-60, E-AB-62158-120, E-AB-62158-200\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: OSM\u003c\/p\u003e\n\n\u003cp\u003eTarget Synonym: OSM\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Cardiovascular,Immunology\u003c\/p\u003e\n\n\u003cp\u003eConjugation: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eSpecies Reactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eApplication: WB, IF\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n \n\n\u003cp\u003eUNIProt ID: P13725\u003c\/p\u003e\n\n\u003cp\u003eBackground: This gene encodes a member of the leukemia inhibitory factor\/oncostatin-M (LIF\/OSM) family of proteins. The encoded preproprotein is proteolytically processed to generate the mature protein. This protein is a secreted cytokine and growth regulator that inhibits the proliferation of a number of tumor cell lines. This protein also regulates the production of other cytokines, including interleukin 6, granulocyte-colony stimulating factor and granulocyte-macrophage colony stimulating factor in endothelial cells. This gene and the related gene, leukemia inhibitory factor, also present on chromosome 22, may have resulted from the duplication of a common ancestral gene. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/mL\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Recombinant fusion protein of human OSM\u003c\/p\u003e\n\n\u003cp\u003eBuffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.\u003c\/p\u003e\n\n\u003cp\u003ePurification Method: Affinity purification\u003c\/p\u003e\n\n\u003cp\u003eDilution: WB 1:500-1:2000, IF 1:50-1:200\u003c\/p\u003e\n\n\u003cp\u003eCalculated MW: 28kDa\u003c\/p\u003e\n\n\u003cp\u003eObserved MW: 28kDa\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C\/One year. Avoid freeze \/ thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eShipping: Ice bag\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"60μL","offer_id":43146228302003,"sku":"E-AB-62158-60","price":280.0,"currency_code":"CAD","in_stock":true},{"title":"120μL","offer_id":43146228334771,"sku":"E-AB-62158-120","price":448.0,"currency_code":"CAD","in_stock":true},{"title":"200μL","offer_id":43146228367539,"sku":"E-AB-62158-200","price":742.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_4cf48081-d186-4fb8-864c-82a20681a066.png?v=1710292004","url":"https:\/\/afsbio.com\/products\/osm-polyclonal-antibody-e-ab-62158","provider":"AFSBio Inc.","version":"1.0","type":"link"}