{"product_id":"osteocalcin-polyclonal-antibody-bs7961","title":"Osteocalcin Polyclonal Antibody-BS7961","description":"\u003cp\u003eOsteocalcin Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50µl, 100µl\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BS7961-50, BS7961-100\u003c\/p\u003e\n\n\u003cp\u003eProduct: Rabbit IgG, 1mg\/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2\u003c\/p\u003e\n\n\u003cp\u003eSwiss-Prot: P02818\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, IF\/ICC\u003c\/p\u003e\n\n\u003cp\u003eAll Applications: WB: 1:500~1:2000\u003cbr\u003e\nIF\/ICC: 1:50~1:200\u003c\/p\u003e\n\n\n\u003cp\u003eBackground: This gene encodes a highly abundant bone protein secreted by osteoblasts that regulates bone remodeling and energy metabolism. The encoded protein contains a Gla (gamma carboxyglutamate) domain, which functions in binding to calcium and hydroxyapatite, the mineral component of bone. Serum osteocalcin levels may be negatively correlated with metabolic syndrome. Read-through transcription exists between this gene and the neighboring upstream gene, PMF1 (polyamine-modulated factor 1), but the encoded protein only shows sequence identity with the upstream gene product.\u003c\/p\u003e\n\n\u003cp\u003ePurification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is \u0026gt; 95% (by SDS-PAGE).\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eSpecificity: Osteocalcin polyclonal antibody detects endogenous levels of Osteocalcin protein.\u003c\/p\u003e\n\n\u003cp\u003eBioworld Molecular Weight: ~ 12 kDa\u003c\/p\u003e\n\n\u003cp\u003eNote: For research use only, not for use in diagnostic procedure.\u003c\/p\u003e\n\n\u003cp\u003eExtra Notes: Western blot analysis of extracts of U-87MG cells, using Osteocalcin antibody at 1:1000 dilution., Western blot analysis of extracts of Rat lung, using Osteocalcin antibody at 1:1000 dilution., Immunofluorescence analysis of MG-63 cells using Osteocalcin pAb at dilution of 1:200 (40x lens)., Immunofluorescence analysis of NIH\/3T3 cells using Osteocalcin pAb at dilution of 1:200 (40x lens).\u003c\/p\u003e\n\n\u003cp\u003eAlternative Name: BGLAP; BGP; OC ; OCN; osteocalcin\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: A synthetic peptide corresponding to a sequence within amino acids 1-100 of human Osteocalcin (BGLAP) (NP_954642.1).\u003c\/p\u003e\n\n\u003cp\u003eConjugate: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eModification: Unmodified\u003c\/p\u003e","brand":"BioWorld","offers":[{"title":"50µl","offer_id":43050221600947,"sku":"BS7961-50","price":342.59,"currency_code":"CAD","in_stock":true},{"title":"100µl","offer_id":43050221633715,"sku":"BS7961-100","price":589.65,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/thumbnail_d1447bac803ec9be_11-14-09-19-51_0db6e7b3-a2b1-4bb6-a01b-906a504f37a2.jpg?v=1707913544","url":"https:\/\/afsbio.com\/products\/osteocalcin-polyclonal-antibody-bs7961","provider":"AFSBio Inc.","version":"1.0","type":"link"}